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Direct linkDean, Olivia M.; Gray, Kylie; Dodd, Seetal; Villagonzalo, Kristi-Ann; Brown, Ellie; Tonge, Bruce; Berk, Michael; Byrne, Linda K. – Journal of Intellectual & Developmental Disability, 2019
Background: Traditional treatment for the behavioural symptoms in autism spectrum disorder (ASD) remains unsatisfactory. There is an urgent need for new, biologically relevant therapies that target both the core and comorbid symptoms that children may experience. This article builds on research previously published by the authors. Method: We…
Descriptors: Autism, Pervasive Developmental Disorders, Intervention, Children
Kent, Justine M.; Kushner, Stuart; Ning, Xiaoping; Karcher, Keith; Ness, Seth; Aman, Michael; Singh, Jaskaran; Hough, David – Journal of Autism and Developmental Disorders, 2013
Efficacy and safety of 2 risperidone doses were evaluated in children and adolescents with autism. Patients (N = 96; 5-17 years), received risperidone (low-dose: 0.125 mg/day [20 to <45 kg], 0.175 mg/day [>45 kg] or high-dose: 1.25 mg/day [20 to <45 kg], 1.75 mg/day [>45 kg]) or placebo. Mean baseline (range 27-29) to endpoint change…
Descriptors: Drug Therapy, Children, Adolescents, Autism
