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Direct linkLatha Valluripalli Soorya; Camille W. Brune; Cristan A. Farmer; Edith V. Ocampo; Natalie I. Berger; Deborah A. Pearson; Robyn M. Busch; Patricia Klaas; Paige Siper; Kristn Currans; Amanda C. Gulsrud; Jennifer M. Phillips; Rajna Filip-Dhima; Sarah E. O’Kelley; Thomas W. Frazier; Tess Levy; Allison L. Wainer; Joseph D. Buxbaum; Craig M. Powell; Jonathan A. Bernstein; Simon K. Warfield; Darcy A. Krueger; E. Martina Bebin; Hope Northrup; Shafali S. Jeste; Alexander Kolevzon; Elizabeth Berry-Kravis; Mustafa Sahin; Siddharth Srivastava; Audrey Thurm – American Journal on Intellectual and Developmental Disabilities, 2025
The Developmental Synaptopathies Consortium is a multisite natural history network studying rare, neurogenetic syndromes associated with synaptic dysfunction and developmental delays. One aim of the Consortium is clinical trial readiness, including identifying clinical concepts and validating their measurement. We evaluated the scope and…
Descriptors: Intellectual Disability, Genetic Disorders, Neurological Impairments, Measurement Techniques
Corti, Claudia; Oldrati, Viola; Storm, Fabio; Bardoni, Alessandra; Strazzer, Sandra; Romaniello, Romina – Journal of Intellectual Disabilities, 2023
Increased attention is arising on the delivery of remote cognitive interventions, which allow performing exercises in everyday settings, favouring rehabilitation continuity. The present study offers an overview of remote cognitive training programs for children with congenital brain malformation or genetic syndrome affecting the central nervous…
Descriptors: Brain, Neurological Impairments, Genetic Disorders, Distance Education
Joyce, Anna; Hill, Catherine M.; Karmiloff-Smith, Annette; Dimitriou, Dagmara – American Journal on Intellectual and Developmental Disabilities, 2019
Sleep plays a key role in the consolidation of newly acquired information and skills into long term memory. Children with Down syndrome (DS) and Williams syndrome (WS) frequently experience sleep problems, abnormal sleep architecture, and difficulties with learning; thus, we predicted that children from these clinical populations would demonstrate…
Descriptors: Sleep, Cognitive Processes, Down Syndrome, Genetic Disorders
Church, Jessica A.; Grigorenko, Elena L.; Fletcher, Jack M. – Reading Research Quarterly, 2023
To learn to read, the brain must repurpose neural systems for oral language and visual processing to mediate written language. We begin with a description of computational models for how alphabetic written language is processed. Next, we explain the roles of a dorsal sublexical system in the brain that relates print and speech, a ventral lexical…
Descriptors: Genetics, Brain Hemisphere Functions, Reading Processes, Oral Language
Commentary: Innovations, Insights, and Impact: Expanding Frontiers in Learning Disabilities Research
McMaster, Kristen L. – New Directions for Child and Adolescent Development, 2019
In this commentary, I highlight key insights from research on learning disabilities (LD) reported in this special issue. Authors of each article describe innovative work that is expanding frontiers of LD knowledge, by focusing on vulnerable and understudied populations, using multiple methodologies and data sources, and building and refining…
Descriptors: Learning Disabilities, Educational Theories, Educational Research, Disproportionate Representation
Van Wert, Hannah; McCabe, Paul C. – Communique, 2022
Conduct disorder (CD) is a pattern of repeated aggression toward others, disregard for the rights of others, and behaviors that violate major social norms at home, in school, and even in society at large (American Psychiatric Association [APA], 2013). Falling under the umbrella of "conduct problems" along with oppositional defiant…
Descriptors: Behavior Disorders, Females, Aggression, Clinical Diagnosis
Vandermosten, Maaike; Correia, Joao; Vanderauwera, Jolijn; Wouters, Jan; Ghesquière, Pol; Bonte, Milene – Developmental Science, 2020
There is an ongoing debate whether phonological deficits in dyslexics should be attributed to (a) less specified representations of speech sounds, like suggested by studies in young children with a familial risk for dyslexia, or (b) to an impaired access to these phonemic representations, as suggested by studies in adults with dyslexia. These…
Descriptors: Brain Hemisphere Functions, Diagnostic Tests, Genetics, Dyslexia
Cazalets, Jean René; Bestaven, Emma; Doat, Emilie; Baudier, Marie Pierre; Gallot, Cécile; Amestoy, Anouck; Bouvard, Manuel; Guillaud, Etienne; Guillain, Isabelle; Grech, Emelyne; Van-gils, Julien; Fergelot, Patricia; Fraisse, Sonia; Taupiac, Emmanuelle; Arveiler, Benoit; Lacombe, Didier – Journal of Autism and Developmental Disorders, 2017
Rubinstein-Taybi syndrome (RTS) is a rare genetic disease that associates intellectual disability with somatic characteristics. We have conducted a study of the overall motor abilities of RTS participants. Static postural performance as well as gait parameters were somewhat decreased, although not significantly compared to typically developing…
Descriptors: Psychomotor Skills, Genetic Disorders, Children, Intellectual Disability
Brankaer, Carmen; Ghesquière, Pol; De Wel, Anke; Swillen, Ann; De Smedt, Bert – Developmental Science, 2017
Cross-syndrome comparisons offer an important window onto understanding heterogeneity in mathematical learning disabilities or dyscalculia. The present study therefore investigated symbolic numerical magnitude processing in two genetic syndromes that are both characterized by mathematical learning disabilities: Turner syndrome and 22q11.2 deletion…
Descriptors: Mathematics Skills, Learning Disabilities, Genetic Disorders, Cognitive Processes
Scaini, Simona; Caputi, Marcella; Ogliari, Anna; Oppo, Annalisa – Journal of Research in Childhood Education, 2020
Literature has shown the importance of social cognition for emotional wellness. However, to our knowledge, few studies so far investigated the relationship between social cognition and anxiety in childhood. No study systematically examined social cognition in relation to specific domains of anxiety. By a correlational design and multivariate…
Descriptors: Genetics, Anxiety Disorders, Social Cognition, Correlation
Margolis, Amy E.; Davis, Katie S.; Pao, Lisa S.; Lewis, Amy; Yang, Xiao; Tau, Gregory; Zhao, Guihu; Wang, Zhishun; Marsh, Rachel – Developmental Science, 2018
Verbal--spatial discrepancies are common in healthy individuals and in those with neurodevelopmental disorders associated with cognitive control deficits including: Autism Spectrum Disorder, Non-Verbal Learning Disability, Fragile X, 22q11 deletion, and Turner Syndrome. Previous data from healthy individuals suggest that the magnitude of the…
Descriptors: Verbal Ability, Spatial Ability, Autism, Pervasive Developmental Disorders
Merker, Sören; Reif, Andreas; Ziegler, Georg C.; Weber, Heike; Mayer, Ute; Ehlis, Ann-Christine; Conzelmann, Annette; Johansson, Stefan; Müller-Reible, Clemens; Nanda, Indrajit; Haaf, Thomas; Ullmann, Reinhard; Romanos, Marcel; Fallgatter, Andreas J.; Pauli, Paul; Strekalova, Tatyana; Jansch, Charline; Vasquez, Alejandro Arias; Haavik, Jan; Ribasés, Marta; Ramos-Quiroga, Josep Antoni; Buitelaar, Jan K.; Franke, Barbara; Lesch, Klaus-Peter – Journal of Child Psychology and Psychiatry, 2017
Background: Attention-deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurodevelopmental disorder with profound cognitive, behavioral, and psychosocial impairments with persistence across the life cycle. Our initial genome-wide screening approach for copy number variants (CNVs) in ADHD implicated a duplication of…
Descriptors: Attention Deficit Hyperactivity Disorder, Neurological Impairments, Genetic Disorders, Physiology
Oerlemans, Anoek M.; Hartman, Catharina A.; Franke, Barbara; Buitelaar, Jan K.; Rommelse, Nanda N. J. – Journal of Autism and Developmental Disorders, 2016
Children with an autism spectrum disorder (ASD) and their unaffected siblings from 54 simplex (SPX, one individual in the family affected) and 59 multiplex (MPX, two or more individuals affected) families, and 124 controls were assessed on intelligence, social cognition and executive functions. SPX and MPX ASD probands displayed similar cognitive…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Siblings
Lanfranchi, Silvia; De Mori, Letizia; Mammarella, Irene C.; Carretti, Barbara; Vianello, Renzo – American Journal on Intellectual and Developmental Disabilities, 2015
The aim of the present study was to compare visuospatial working memory performance in 18 individuals with Williams syndrome (WS) and 18 typically developing (TD) children matched for nonverbal mental age. Two aspects were considered: task presentation format (i.e., spatial-sequential or spatial-simultaneous), and level of attentional control…
Descriptors: Genetic Disorders, Disabilities, Visual Perception, Spatial Ability
Lehnhardt, Fritz-Georg; Falter, Christine Michaela; Gawronski, Astrid; Pfeiffer, Kathleen; Tepest, Ralf; Franklin, Jeremy; Vogeley, Kai – Journal of Autism and Developmental Disorders, 2016
Females with high-functioning ASD are known to camouflage their autistic symptoms better than their male counterparts, making them prone to being under-ascertained and delayed in diagnostic assessment. Thus far the underlying cognitive processes that enable such successful socio-communicative adaptation are not well understood. The current results…
Descriptors: Females, Genetics, Autism, Pervasive Developmental Disorders
