Introduction: Down Syndrome (DS) is a common cause of intellectual disability with a possible glial-neuronal disruption. We assessed the effects of Cerebrolysin on the neurodevelopmental outcomes of infants with DS. Methods: This randomized controlled pilot trial included 64 infants with DS. They were allocated into a treatment group (n=32) who…

Background: Sleep affects children's cognitive development, preparedness for school and future academic outcomes. People with Down syndrome (DS) are particularly at risk for sleep-disordered breathing (SDB). To our knowledge, the association between SDB and cognition in preschoolers with DS is unknown. Methods: We assessed sleep by using…

An early intervention program for 14 Down's syndrome children (4 to 15 months old) and their parents included individualized guidance for parents in teaching their infant. Home activities centered on tasks to develop attention: cognitive, perceptual, motor, and language skills. Emphasis was placed on a structured teaching approach with…

The book offers 14 papers presented at two conferences on assessment and intervention with handicapped infants, sponsored by the Western States Technical Assistance Resource. Titles and authors include: "Neonatal Diagnosis of the Neurologically Handicapped" (M. Coleman); "Principles of Infant Assessment" (J. Swanson); "Focus on the Parent-Infant…