Enrichment in rodents affects brain structure, improves behavioral performance, and is neuroprotective. Similarly, in humans, according to the cognitive reserve concept, enriched experience is functionally protective against neuropathology. Despite this parallel, the ability to translate rodent studies to human clinical situations is limited. This…

Individuals with autism spectrum disorder (ASD) show atypical processing of facial expressions. Research with autistic toddlers suggests that abnormalities in processing of spatial frequencies (SFs) contribute to such differences. The current event-related-potential (ERP) study investigated differences between 10-month-old infants with high- and…

Infants' perception of faces becomes attuned to the environment during the first year of life. However, the mechanisms that underpin perceptual narrowing for faces are only poorly understood. Considering the developmental similarities seen in perceptual narrowing for faces and speech and the role that statistical learning has been shown to play…

Younger brains are noisier information processing systems; this means that information for younger individuals has to allow clearer differentiation between those aspects that are required for the processing task in hand (the "signal") and those that are not (the "noise"). We compared toddler-directed and adult-directed TV…

The effects of individual versus category training, using behavioral indices of stimulus discrimination and neural ERPs indices of holistic processing, were examined in infants. Following pretraining assessments at 6 months, infants were sent home with training books of objects for 3 months. One group of infants was trained with six different…

It has been recently argued that some machine learning techniques known as Kernel methods could be relevant for capturing cognitive and neural mechanisms (Jakel, Scholkopf, & Wichmann, 2009). We point out that "String kernels," initially designed for protein function prediction and spam detection, are virtually identical to one contending proposal…

The current authors reply to a response by Bowers on a comment by the current authors on the original article. A typical problem in any discussion about grandmother cells is that there is not a general consensus about what should be called as such. Here, we discuss possible interpretations in turn and contrast them with what we find in our own…

The author briefly responds to a number of terminological, theoretical, and empirical issues raised in some postscripts. The goal is not to respond to each outstanding point but rather to address some comments that in his view confuse rather than clarify matters. He responds to Plaut and McClelland and Quian Quiroga and Kreiman in turn.

Event-related brain potentials (ERPs) were recorded while participants (n=13) were presented with mirrored and normal letters at different orientations and were asked to make mirror-normal letter discriminations. As it has been suggested that a mental rotation out of the plane might be necessary to decide on mirrored letters, we wanted to…

Plaut and McClelland (2010) and Quian Quiroga and Kreiman both challenged my characterization of localist and distributed representations. They also challenged the biological plausibility of grandmother cells on conceptual and empirical grounds. This reply addresses these issues in turn. The premise of my argument is that grandmother cells in…

Williams Syndrome (WS) is a rare neurodevelopmental disorder, which stems from a genetic deletion on chromosome 7 and causes a profound weakness in visuospatial cognition. Our current study explores how orientation perception may contribute to the visuospatial deficits in WS. In Experiment 1, we found that WS individuals and normal 3-4 year olds…

In cross-dimensional visual search tasks, target discrimination is faster when the previous trial contained a target defined in the same visual dimension as the current trial. The dimension-weighting account (DWA; A. Found & H. J. Muller, 1996) explains this intertrial facilitation by assuming that visual dimensions are weighted at an early…

Background: Standardised neuropsychological and cognitive measures present some limitations in their applicability and generalisability to individuals with intellectual disability (ID). Alternative approaches to defining the cognitive signatures of various forms of ID are needed to advance our understanding of the profiles of strengths and…

The present study used event-related potentials (ERPs) to determine the degree to which people can process words while devoting central attention to another task. Experiments 1-4 measured the N400 effect, which is sensitive to the degree of mismatch between a word and the current semantic context. Experiment 5 measured the P3 difference between…

Three experiments were carried out to investigate hemispheric asymmetry in color processing among normal participants. In Experiment 1, it was shown that the reaction times (RTs) of the dominant and non-dominant hands assessed using a visual target presented at the central visual field, were not significantly different. In Experiment 2, RTs of…