Although the basolateral amygdala (BLA) plays a crucial role for the acquisition of fear memories, sensory cortices are involved in their long-term storage in rats. However, the time course of their respective involvement has received little investigation. Here we assessed the role of the glutamatergic N-methyl-D-aspartate (NMDA) receptors in the…

There is growing interest in generalization of learned contextual fear, driven in part by the hypothesis that mood and anxiety disorders stem from impaired hippocampal mechanisms of fear generalization and discrimination. However, there has been relatively little investigation of the behavioral and procedural mechanisms that might control…

To test the selectivity of the orexin A (OXA) system in olfactory sensitivity, the present study compared the effects of fasting and of central infusion of OXA on the memory processes underlying odor-malaise association during the conditioned odor aversion (COA) paradigm. Animals implanted with a cannula in the left ventricle received ICV infusion…

We report here that ZIP, a selective inhibitor of the atypical protein kinase C isoform PKM[zeta], abolishes very long-term conditioned taste aversion (CTA) associations in the insular cortex of the behaving rat, at least 3 mo after encoding. The effect of ZIP is not replicated by a general serine/threonine protein kinase inhibitor that is…

Western psychologists define "set" as a group of items, a disposition toward certain stimuli or certain responses, and the establishment of habitual actions. D. N. Uznadze explains "set" by postulating a general tendency toward habitual action, but qualifies this by stating that the tendency is governed by special factors…

Evidence that the vigor of the startle reflex varies systematically with the organism's emotional state is reviewed. A theory elucidating this relationship suggests how amplitude of eyeblink response to a probe may be modulated by affective content of perception and thought. Implications for research on emotion are outlined. (SLD)

When a visual target is identified, there is a period of several hundred milliseconds when the processing of subsequent targets is impaired, a phenomenon labeled the attentional blink (AB). The emerging consensus is that the identification of a visual target temporarily occupies a limited attentional resource that is essential for all visual…

Data are presented from two experiments investigating whether covert responses can be modified. Imagery was chosen as a target because of its significant role in behavior therapy techniques. Resent evidence on the facilitative effects of imagery in paired-associate learning suggested to the experimenters the use of performance on a…

Imaginal perspective switches are often considered to be difficult, because they call for additional cognitive transformations of object coordinates (transformation hypothesis). Recent research suggests that problems can also result from conflicts between incompatible sensorimotor and cognitive object location codes during response specification…

One control group and eight experimental groups, each composed of 12 first grade children, participated in this experiment. It was designed to investigate the effects of frequency of reinforcement and repeated evaluation of stimuli on the conditioning of preferences. Each child participated in the experiment for seven consecutive school days. The…