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Cheng, Jingjun; Feenstra, Matthijs G. P. – Learning & Memory, 2006
Combined activation of dopamine D1- and NMDA-glutamate receptors in the nucleus accumbens has been strongly implicated in instrumental learning, the process in which an individual learns that a specific action has a wanted outcome. To assess dopaminergic activity, we presented rats with two sessions (30 trials each) of a one-lever appetitive…
Descriptors: Rewards, Biochemistry, Nonverbal Learning, Animals
Yin, Henry H.; Knowlton, Barbara J. – Learning & Memory, 2004
The involvement of different subregions of the striatum in place and response learning was examined using a T-maze. Rats were given NMDA lesions of the dorsolateral striatum (DLS), anterior dorsomedial striatum (ADMS), posterior dorsomedial striatum (PDMS), or sham surgery. They were then trained to retrieve food from the west arm of the maze,…
Descriptors: Nonverbal Learning, Behavioral Science Research, Neurological Impairments, Spatial Ability