Described is the author's decision to help a student find alternatives to performing several terminal experiments on animals in a college physiology class. Replacement exercises used for studying the properties of muscle types are described. Details about the difficulties and successes of the entire experience are reported. (KR)

A computer program that replaces a set of pharmacology and physiology laboratory experiments on live animals or isolated organs is described and illustrated. Five experiments are simulated: dose-effect relationships on smooth muscle, blood pressure and catecholamines, neuromuscular signal transmission, acetylcholine and the circulation, and…

Three interactive computer-assisted learning programs are described. The use of tissues from freshly killed frogs is simulated, including the isolated sciatic nerve, the sciatic nerve-gastrocnemius muscle, and the in situ heart. (KR)