The pandemic COVID-19 has brought the closure of schools of all levels and all universities in Italy, since early March 2020 up to the end of the teaching period (first half of June 2020). However, almost all universities guaranteed the continuity of educational and professional courses by using several distance education modalities. The purpose of this communication is to describe how a course of History of Chemistry and Basics of Chemical Education for first-year undergraduate students was reorganized and delivered during the COVID-19 emergency and to share several considerations that might be useful for the future. Positive and negative aspects emerged during this distance education experience are finally reported.