Owing to the critical role of stereochemistry in biotechnology, medicine, and industry, it must be well represented in undergraduate lab curricula. To achieve these stereochemical laboratory requirements without sacrificing existing lab techniques, we modified two standard laboratory experiments to include chiral GC analysis as follows. (1) The…

The ability to elucidate the structure of organic compounds from their nuclear magnetic resonance (NMR), infrared (IR), and mass spectrometry (MS) spectra is an essential skill, particularly for those engaged in the fields of synthetic and analytical organic chemistry. Spectral analysis constitutes a fundamental component of the curriculum for all…

Colloidal stability is one of the most important criteria in the application strategy of colloidal nanoparticles in the continuous phase. The branches include ecology, involving coagulation as a purification method; medicine as nanocarriers; biology as blood coagulation, etc. A chemist versed in these concepts is a high-performing chemist in…

The American Chemical Society advocates a shift from rule-based to risk-based safety education for chemistry graduates, emphasizing meaningful student engagement in the risk assessment process for laboratory work. To implement this paradigm shift, we introduced RAMP (Recognize Hazards, Assess Risk, Minimize Risk, and Prevent Emergencies)-based…

Chemometric techniques such as partial least-squares (PLS) regression have been applied with huge success to a wide array of chemical problems including multicomponent analysis of analytes in complex mixtures. Despite this, there are few examples of laboratory pedagogical exercises that involve students in the acquisition of chemical data from…

Plant extracts and their components have been reported to have antimicrobial properties against phytopathogens. Although such properties could be harnessed for the development of new pathogen control strategies, there are no standardised methods for their assessment in different extracts. The laboratory exercise presented here involves the use of…

An organic chemistry experiment designed for senior undergraduates focuses on bifunctional catalysis, a critical yet often omitted topic at the undergraduate level, but essential for advanced studies in chemistry. By utilization of a tertiary amine-thiourea catalyst in the asymmetric Michael addition reaction, the experiment showcases the…

A renewed experimental procedure for the unknown carbonyl experiment has been developed using hydrazone synthesis, thin layer chromatography (TLC) analysis, and melting point determination to differentiate between structurally similar ketones and aldehydes in undergraduate organic chemistry practical courses. Benzaldehyde, p-tolualdehyde,…

Teaching graduate students the entanglements of the interdisciplinary field of electrochemical DNA biosensors in microfluidics can be challenging, as it involves multiple fields of research strongly interacting with each other. Yet, electrochemical biosensors coupled with the improved hydrodynamics of microfluidics allow for simpler, more…

Chemists have always designed and deployed cross-disciplinary approaches that interface chemistry with other disciplines to proffer solutions to many human problems. We designed a laboratory experiment that implements chemistry concepts in a biological model to prime undergraduate students to appreciate interdisciplinarity as an approach to…

The essential component of expanding an undergraduate curriculum is the inclusion of lab experiments in nanoscience and nanomaterials, which significantly impact health and the environment through their use in food, cosmetics, agriculture, and medicine. We designed a laboratory experiment based on the atomic force microscopy (AFM) analysis of the…

A multicomponent reaction was adapted and successfully applied in the major organic course, which involves synthesizing and characterizing a 1,3-benzoxazine derived from paracetamol extracted from tablets of the worldwide well-known medicine Tylenol. Using paracetamol as a reagent is a motivational strategy in undergraduate laboratories to meet…

Heart muscle cells, or cardiomyocytes, exhibit intrinsic contractility in vitro. We found that commercially-available mammalian cardiomyocytes serve as an excellent model system for studying the cytoskeleton and cellular contractility, fundamental topics in undergraduate cell and molecular biology courses. Embryonic rat cardiomyocytes were plated…

This article details the outcome of a joint reflective approach undertaken by the authors to identify common difficulties experienced by 2nd-year undergraduate Biochemistry students in laboratory classes. Difficulties experienced in laboratories can affect the development of hand skills, an understanding of how to correctly operate laboratory…

The substitution of carbonyl compounds with liquid bromine as a brominating agent is the most commonly employed synthesis method for a-bromoacetophenone and its derivatives. However, liquid bromine possesses certain drawbacks, such as volatilization, high toxicity, strong corrosion, and poor reaction selectivity, which limit its application and…