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Direct linkGodolphin, Peter J.; White, Ian R.; Tierney, Jayne F.; Fisher, David J. – Research Synthesis Methods, 2023
Estimation of within-trial interactions in meta-analysis is crucial for reliable assessment of how treatment effects vary across participant subgroups. However, current methods have various limitations. Patients, clinicians and policy-makers need reliable estimates of treatment effects within specific covariate subgroups, on relative and absolute…
Descriptors: Meta Analysis, Outcomes of Treatment, Medical Research, Comparative Analysis
Jackson, Dan; Rollins, Katie; Coughlin, Patrick – Research Synthesis Methods, 2014
Motivated by our meta-analytic dataset involving survival rates after treatment for critical leg ischemia, we develop and apply a new multivariate model for the meta-analysis of study level survival data at multiple times. Our data set involves 50 studies that provide mortality rates at up to seven time points, which we model simultaneously, and…
Descriptors: Multivariate Analysis, Meta Analysis, Mortality Rate, Comparative Analysis
Stansfield, Claire; Thomas, James; Kavanagh, Josephine – Research Synthesis Methods, 2013
Background: Scoping reviews of research help determine the feasibility and the resource requirements of conducting a systematic review, and the potential to generate a description of the literature quickly is attractive. Aims: To test the utility and applicability of an automated clustering tool to describe and group research studies to improve…
Descriptors: Case Studies, Comparative Analysis, Research Reports, Feasibility Studies
