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Fahim, Cherine; Meguid, Nagwa A.; Nashaat, Neveen H.; Yoon, Uicheul; Mancini-Marie, Adham; Evans, Alan C. – Research in Autism Spectrum Disorders, 2012
The autism phenotype is associated with an excess of brain volume due in part to decreased pruning during development. Here we aimed at assessing brain volume early in development to further elucidate previous findings in autism and determine whether this pattern is restricted to idiopathic autism or shared within the autistic phenotype (fragile X…
Descriptors: Mental Retardation, Autism, Neurology, Brain
Han, Yvonne M. Y.; Chan, Agnes S.; Sze, Sophia L.; Cheung, Mei-Chun; Wong, Chun-kwok; Lam, Joseph M. K.; Poon, Priscilla M. K. – Research in Autism Spectrum Disorders, 2013
Previous studies have shown that children with autism spectrum disorders (ASDs) have impaired executive function, disordered neural connectivity, and abnormal immunologic function. The present study examined whether these abnormalities were associated. Seventeen high-functioning (HFA) and 17 low-functioning (LFA) children with ASD, aged 8-17…
Descriptors: Metabolism, Brain Hemisphere Functions, Autism, Foreign Countries
Doyle-Thomas, Krissy A. R.; Duerden, Emma G.; Taylor, Margot J.; Lerch, Jason P.; Soorya, Latha V.; Wang, A. Ting; Fan, Jin; Hollander, Eric; Anagnostou, Evdokia – Research in Autism Spectrum Disorders, 2013
Several brain regions show structural and functional abnormalities in individuals with autism spectrum disorders (ASD), but the developmental trajectory of abnormalities in these structures and how they may relate to social and communicative impairments are still unclear. We assessed the effects of age on cortical thickness in individuals with…
Descriptors: Autism, Pervasive Developmental Disorders, Brain Hemisphere Functions, Age Differences
Iwanami, Akira; Okajima, Yuka; Ota, Haruhisa; Tani, Masayuki; Yamada, Takashi; Hashimoro, Ryuichiro; Kanai, Chieko; Watanabe, Hiromi; Yamasue, Hidenori; Kawakubo, Yuki; Kato, Nobumasa – Research in Autism Spectrum Disorders, 2011
Dysfunction of the prefrontal cortex has been previously reported in individuals with Asperger's disorder. In the present study, we used multi-channel near-infrared spectroscopy (NIRS) to detect changes in the oxygenated hemoglobin concentration ([oxy-Hb]) during two verbal fluency tasks. The subjects were 20 individuals with Asperger's disorder…
Descriptors: Asperger Syndrome, Spectroscopy, Brain Hemisphere Functions, Diagnostic Tests
Senju, Atsushi; Kikuchi, Yukiko; Akechi, Hironori; Hasegawa, Toshikazu; Tojo, Yoshikuni; Osanai, Hiroo; Johnson, Mark H. – Research in Autism Spectrum Disorders, 2011
Atypical development of face processing is a major characteristic in autism spectrum disorder (ASD), which could be due to atypical interactions between subcortical and cortical face processing. The current study investigated the saccade planning towards faces in ASD. Seventeen children with ASD and 17 typically developing (TD) children observed a…
Descriptors: Autism, Pervasive Developmental Disorders, Visual Perception, Cognitive Processes
Ishitobi, Makoto; Kosaka, Hirotaka; Omori, Masao; Matsumura, Yukiko; Munesue, Toshio; Mizukami, Kimiko; Shimoyama, Tomohiro; Murata, Tetsuhito; Sadato, Norihiro; Okazawa, Hidehiko; Wada, Yuji – Research in Autism Spectrum Disorders, 2011
Much functional neuroimaging evidence indicates that autistic spectrum disorders (ASD) demonstrate marked brain abnormalities in face processing. Most of these findings were obtained from studies using tasks related to whole faces. However, individuals with ASD tend to rely more on individual parts of the face for identification than on the…
Descriptors: Cognitive Processes, Autism, Attention, Patients
Chan, Agnes S.; Han, Yvonne M. Y.; Sze, Sophia L.; Cheung, Mei-chun; Leung, Winnie Wing-man; Chan, Raymond C. K.; To, Cho Yee – Research in Autism Spectrum Disorders, 2011
The present study examined the memory performance and cortical connectivity of children with ASD, and investigated whether the memory deficits exhibited by these children were associated with the cortical connectivity. Twenty-one children with ASD and 21 children with normal development (NC), aged 5-14 years, participated in the study. Each child…
Descriptors: Autism, Memory, Memorization, Pervasive Developmental Disorders
Yamasaki, Takao; Fujita, Takako; Ogata, Katsuya; Goto, Yoshinobu; Munetsuna, Shinji; Kamio, Yoko; Tobimatsu, Shozo – Research in Autism Spectrum Disorders, 2011
People with autism spectrum disorder (ASD) often show inferior global motion performance with superior performance in detail form perception, suggesting dysfunction of the dorsal visual stream. To elucidate the neural basis of impaired global motion perception in ASD, we measured psychophysical threshold and visual event-related potentials (ERPs)…
Descriptors: Visual Stimuli, Autism, Motion, Pervasive Developmental Disorders
Chan, Agnes S.; Han, Yvonne M. Y.; Leung, Winnie Wing-man; Leung, Connie; Wong, Virginia C. N.; Cheung, Mei-chun – Research in Autism Spectrum Disorders, 2011
Previous studies showed that the anterior cingulate cortex (ACC) is activated when individuals engage in attention and inhibitory control tasks. The present study examined whether ACC activity is associated with behavioral performance of the two tasks. Twenty normal and 20 children with autism spectrum disorders (ASDs) were subjected to…
Descriptors: Autism, Brain Hemisphere Functions, Attention Span, Inhibition
Haesen, Birgitt; Boets, Bart; Wagemans, Johan – Research in Autism Spectrum Disorders, 2011
This literature review aims to interpret behavioural and electrophysiological studies addressing auditory processing in children and adults with autism spectrum disorder (ASD). Data have been organised according to the applied methodology (behavioural versus electrophysiological studies) and according to stimulus complexity (pure versus complex…
Descriptors: Autism, Auditory Perception, Pervasive Developmental Disorders, Speech Communication
Kouijzer, Mirjam E. J.; van Schie, Hein T.; de Moor, Jan M. H.; Gerrits, Berrie J. L.; Buitelaar, Jan K. – Research in Autism Spectrum Disorders, 2010
Effects of neurofeedback treatment were investigated in children with autism spectrum disorders (ASD). Sixty percent of the participants in the treatment group successfully reduced excessive theta power during neurofeedback treatment. Reduction of theta power was confirmed by pre- and post-QEEG measures. Parents of participants in the…
Descriptors: Control Groups, Autism, Communication Skills, Neurological Impairments
Lewis, Fiona M.; Woodyatt, Gail C.; Murdoch, Bruce E. – Research in Autism Spectrum Disorders, 2008
This article reports on the linguistic and pragmatic language skills of adults with a diagnosis of autism spectrum disorder (ASD). Seventeen adults (aged 18-67 years) with a diagnosis of ASD were assessed using the Western Aphasia Battery (WAB), the Right Hemisphere Language Battery (RHLB) and the Test of Nonverbal Intelligence-Second Edition…
Descriptors: Adults, Multivariate Analysis, Language Skills, Nonverbal Ability