The study sought to examine developmental processes of substitution in the pretend play of Down's syndrome children and to clarify the onset mechanism of subskills in decontextualization, which refers to the progress from imitation to substitution and then to invention. Eighteen Japanese children, aged 29-55 months, with Down's syndrome were given…

The physical and neurobehavioral findings at 3 years of age for 39 children born to mothers on methadone- maintenance and 23 children born to drug-free comparison mothers are reported. The methadone children had a higher incidence of head circumferences less than the third percentile, nystagmus/strabismus, and otitis media. No differences were…