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Direct linkRoyston, R.; Oliver, C.; Moss, J.; Adams, D.; Berg, K.; Burbidge, C.; Howlin, P.; Nelson, L.; Stinton, C.; Waite, J. – Journal of Autism and Developmental Disorders, 2018
This study describes the profile of repetitive behaviour in individuals with Williams syndrome, utilising cross-syndrome comparisons with people with Prader-Willi and Down syndromes. The Repetitive Behaviour Questionnaire was administered to caregivers of adults with Williams (n = 96), Prader-Willi (n = 103) and Down (n = 78) syndromes. There were…
Descriptors: Comparative Analysis, Down Syndrome, Intelligence Quotient, Questionnaires
Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Toseeb, Umar; Oginni, Olakunle Ayokunmi; Dale, Philip S. – Journal of Learning Disabilities, 2022
There is considerable variability in the extent to which young people with developmental language disorder (DLD) experience mental health difficulties. What drives these individual differences remains unclear. In the current article, data from the Twin Early Development Study were used to investigate the genetic and environmental influences on…
Descriptors: Language Impairments, Correlation, Psychopathology, Mental Health
Download full textElizabeth A. Shewark; Amanda M. Ramos; Chang Liu; Jody M. Ganiban; Gregory Fosco; Daniel S. Shaw; David Reiss; Misaki N. Natsuaki; Leslie D. Leve; Jenae M. Neiderhiser – Grantee Submission, 2021
Background: Evocative gene-environment correlation (rGE) describes a process through which children's heritable characteristics influence their rearing environments. The current study examined if heritable influences on parenting and children's behavioral outcomes operate through child negative emotionality. Method: Using data from the Early…
Descriptors: Parent Child Relationship, Correlation, Genetics, Child Rearing
Raza, Sarah; Sacrey, Lori-Ann R.; Zwaigenbaum, Lonnie; Bryson, Susan; Brian, Jessica; Smith, Isabel M.; Roberts, Wendy; Szatmari, Peter; Vaillancourt, Tracy; Roncadin, Caroline; Garon, Nancy – Journal of Autism and Developmental Disorders, 2020
Social-emotional behavior in autism spectrum disorder (ASD) was examined among high-risk (HR; siblings of children diagnosed with ASD) and low-risk (LR; no family history of ASD) toddlers. Caregivers completed the Infant-Toddler Social Emotional Assessment (ITSEA) at 18 months, and blind diagnostic assessment for ASD was conducted at 36 months.…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Clinical Diagnosis
Whitten, Allison; Unruh, Kathryn E.; Shafer, Robin L.; Bodfish, James W. – Journal of Autism and Developmental Disorders, 2018
Existing models of autism spectrum disorder (ASD) disagree as to whether the core features should be conceptualized as convergent (related) or divergent (unrelated), and the few previous studies addressing this question have found conflicting results. We examined standardized parent ratings of symptoms from three domains (social, communication,…
Descriptors: Autism, Symptoms (Individual Disorders), Pervasive Developmental Disorders, Genetics
Dimitropoulos, Anastasia; Ho, Alan; Feldman, Benjamin – Journal of Autism and Developmental Disorders, 2013
Prader-Willi syndrome (PWS), a neurodevelopmental disorder primarily characterized by hyperphagia and food preoccupations, is caused by the absence of expression of the paternally active genes in the proximal arm of chromosome 15. Although maladaptive behavior and the cognitive profile in PWS have been well characterized, social functioning has…
Descriptors: Prosocial Behavior, Genetics, Interpersonal Competence, Autism
Lough, Emma; Hanley, Mary; Rodgers, Jacqui; South, Mikle; Kirk, Hannah; Kennedy, Daniel P.; Riby, Deborah M. – Journal of Autism and Developmental Disorders, 2015
Interpersonal distance regulation is crucial for successful social interactions. We investigated personal space awareness in Williams syndrome (WS) and autism spectrum disorder (ASD) compared to typical development. Parents reported that individuals with WS and ASD were significantly more likely than those developing typically to invade the…
Descriptors: Autism, Pervasive Developmental Disorders, Genetic Disorders, Personal Space
Thurman, Angela John; McDuffie, Andrea; Kover, Sara T.; Hagerman, Randi J.; Abbeduto, Leonard – Journal of Autism and Developmental Disorders, 2015
Although males with fragile X syndrome (FXS) are frequently described as demonstrating autism symptomatology, there is much debate regarding whether the behavioral symptoms representing the core domains of autism are the result of the same or different underlying neurological/psychological mechanisms. The present study used a cross-sectional…
Descriptors: Males, Genetic Disorders, Autism, Pervasive Developmental Disorders
Hahn, Laura J.; Fidler, Deborah J.; Hepburn, Susan L. – American Journal on Intellectual and Developmental Disabilities, 2014
The present study compares the adaptive behavior profile of 18 young children with Williams syndrome (WS) and a developmentally matched group of 19 children with developmental disabilities and examines the relationship between adaptive behavior and problem behaviors in WS. Parents completed the Vineland Adaptive Behavioral Scales--Interview…
Descriptors: Genetic Disorders, Behavior Problems, Young Children, Comparative Analysis
Williams, Tracey A.; Porter, Melanie A.; Langdon, Robyn – Journal of Autism and Developmental Disorders, 2013
Fragile X syndrome (FXS) and Williams syndrome (WS) are both genetic disorders which present with similar cognitive-behavioral problems, but distinct social phenotypes. Despite these social differences both syndromes display poor social relations which may result from abnormal social processing. This study aimed to manipulate the location of…
Descriptors: Genetic Disorders, Congenital Impairments, Mental Retardation, Attention
Cianfaglione, Rina; Hastings, Richard P.; Felce, David; Clarke, Angus; Kerr, Michael P. – Journal of Autism and Developmental Disorders, 2015
Few published studies have reported on the psychological well-being of family members of individuals with Rett syndrome (RTT). Eighty-seven mothers of girls and women with RTT completed a questionnaire survey about their daughters' behavioral phenotype, current health, and behavior problems, and their own and a sibling's well-being. Mothers…
Descriptors: Well Being, Mothers, Daughters, Genetic Disorders
Arron, K.; Oliver, C.; Moss, J.; Berg, K.; Burbidge, C. – Journal of Intellectual Disability Research, 2011
Background: Self-injurious and aggressive behaviours are reported as components of some behavioural phenotypes but there are few studies comparing across syndrome groups. In this study we examined the prevalence of these behaviours and the associated person characteristics in seven genetic syndromes. Methods: Questionnaire data on self-injury and…
Descriptors: At Risk Persons, Intervention, Incidence, Injuries
May, Michael E.; Brandt, Rachel C.; Bohannan, Joseph K. – Intellectual and Developmental Disabilities, 2012
Advances in gene-environment interaction research have revealed genes that are associated with aggression. However, little is known about parent perceptions of genetic screening for behavioral symptoms like aggression as opposed to diagnosing disabilities. These perceptions may influence future research endeavors involving genetic linkage studies…
Descriptors: Genetics, Autism, Early Intervention, Parent Attitudes
van Hulst, Branko M.; de Zeeuw, Patrick; Bos, Dienke J.; Rijks, Yvonne; Neggers, Sebastiaan F. W.; Durston, Sarah – Journal of Child Psychology and Psychiatry, 2017
Background: Changes in reward processing are thought to be involved in the etiology of attention-deficit/hyperactivity disorder (ADHD), as well as other developmental disorders. In addition, different forms of therapy for ADHD rely on reinforcement principles. As such, improved understanding of reward processing in ADHD could eventually lead to…
Descriptors: Attention Deficit Hyperactivity Disorder, Task Analysis, Reinforcement, Therapy
