The functional neuroanatomy of language localization in dyslexia has primarily been studied in the context of reading. However, dyslexia is sometimes referred to as a "language-based learning disability," yet the functional signature of the core language comprehension network in dyslexia is far less understood. This thesis presents a…

This study characterizes the subcortical auditory brainstem response (speech-ABR) and cortical auditory processing (P1 and Mismatch Negativity; MMN) to speech sounds and their relationship to autistic traits and sensory features within the same group of autistic children (n = 10) matched on age and non-verbal IQ to their typically developing (TD)…

The lexical representation of compound words in speech production is still under debate. While most studies with healthy adult speakers suggest that a single lemma representation is active during compound production, data from neuropsychological studies point toward multiple representations, with activation of the compound's constituent lemmas in…

The long-term objective of this project was to better understand how shorter auditory experience and spectral degradation of the cochlear implant (CI) signal impact spoken language processing in deaf children with CIs. The specific objective of this research was to utilize psycholinguistic methods to investigate the mechanisms underlying observed…

Primary progressive aphasia (PPA) is an acquired neurodegenerative syndrome that has specific and devastating effects on an individual's speech and language ability. Based on a detailed assessment of behavior and cognition, combined with structural neuroimaging data and pathological evidence, PPA is typically classified into three variants: the…

Purpose: Miniaturization of digital technologies has created new opportunities for remote health care and neuroscientific fieldwork. The current study assesses comparisons between in-home auditory brainstem response (ABR) recordings and recordings obtained in a traditional lab setting. Method: Click-evoked and speech-evoked ABRs were recorded in…

Purpose: The aim of this study was to quantify changes in speech intelligibility in two cohorts of people with Parkinson's disease (PD; those with and without deep brain stimulation [DBS]) across a broad range of self-selected speech rate alterations in: (1) read sentences; and (2) extemporaneous speech (monologues). Method: Four speaker groups…

In this work we ask whether at birth, the human brain responds uniquely to speech, or if similar activation also occurs to a non-speech surrogate 'language'. We compare neural activation in newborn infants to the language heard "in utero" (English), to an unfamiliar language (Spanish), and to a whistled surrogate language (Silbo Gomero)…

Purpose: Cognition and language difficulties are frequently reported in both children and adults with epilepsy. The majority of the existing research has focused on pediatric epilepsy, documenting impairments in learning, academics, and social-emotional functioning. In comparison, language deficits in younger and older adults with epilepsy have…

There is an ongoing debate whether phonological deficits in dyslexics should be attributed to (a) less specified representations of speech sounds, like suggested by studies in young children with a familial risk for dyslexia, or (b) to an impaired access to these phonemic representations, as suggested by studies in adults with dyslexia. These…

Purpose: Investigations into the nature of communication disorders in autistic individuals increasingly evaluate neural responses to speech stimuli. This integrative review aimed to consolidate the available data related to speech and language processing across levels of stimulus complexity (from single speech sounds to sentences) and to relate it…

Purpose: Recent findings in preschool children indicated novel adjective recall was enhanced when learned using repeated retrieval with contextual reinstatement (RRCR) compared to repeated study (RS). Recall was similar for learned pictures used during training and new (generalized) pictures with the same adjective features. The current study…

Purpose: Rapid maximum performance repetition tasks have increasingly demonstrated their utility as clinimetric markers supporting diagnosis and monitoring of bulbar disease in amyotrophic lateral sclerosis (ALS). A recently developed protocol uses novel real-word repetitions instead of traditional nonword/syllable sequences in hopes of improving…

Purpose: Right hemisphere brain damage (RHD) commonly causes pragmatic language disorders that are apparent in discourse production. Specific characteristics and approaches to assessment, diagnosis, and treatment of these disorders are not well-defined. RHDBank, a shared database of multimedia interactions for the study of communication using…

Purpose: An impoverished production of routinized expressions, namely, formulaic language, has been reported for monolingual speakers with Parkinson's disease (PD). Little is known regarding how formulaic expressions might be manifested in individuals with neurological damage who speak more than one language. This study investigated the processing…