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Cost-Effectiveness Analysis Comparing Pre-Diagnosis Autism Spectrum Disorder (ASD)-Targeted Intervention with Ontario's Autism Intervention Program
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Penner, Melanie; Rayar, Meera; Bashir, Naazish; Roberts, S. Wendy; Hancock-Howard, Rebecca L.; Coyte, Peter C. – Journal of Autism and Developmental Disorders, 2015
Novel management strategies for autism spectrum disorder (ASD) propose providing interventions before diagnosis. We performed a cost-effectiveness analysis comparing the costs and dependency-free life years (DFLYs) generated by pre-diagnosis intensive Early Start Denver Model (ESDM-I); pre-diagnosis parent-delivered ESDM (ESDM-PD); and the Ontario…
Descriptors: Foreign Countries, Autism, Pervasive Developmental Disorders, Clinical Diagnosis
Mechanisms of Developmental Regression in Autism and the Broader Phenotype: A Neural Network Modeling Approach
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Thomas, Michael S. C.; Knowland, Victoria C. P.; Karmiloff-Smith, Annette – Psychological Review, 2011
Loss of previously established behaviors in early childhood constitutes a markedly atypical developmental trajectory. It is found almost uniquely in autism and its cause is currently unknown (Baird et al., 2008). We present an artificial neural network model of developmental regression, exploring the hypothesis that regression is caused by…
Descriptors: Autism, Language Impairments, Prediction, Developmental Stages