The current organic synthesis program at Harvard University is called the Logic and Heuristics Applied to Synthetic Analysis (LHASA). Discusses this program in detail, focusing on retrosynthetic analysis approach, LHASA hardware, graphical input/perception, strategy control, transform evaluation, and LHASA enhancement. (JN)

Discusses use and applications of computer technology in chemistry, indicating that the importance of the computer has not been fully realized in the realm of organic synthesis. Includes discussions of various computer programs and systems currently used, supplemented by tables highlighting, for example, features of major computer-aided synthesis…