Discusses client-server architecture in dumb terminals, personal computers, local area networks, and graphical user interfaces. Focuses on functions offered by client personal computers: individualized environments; flexibility in running operating systems; advanced operating system features; multiuser environments; and centralized data…

Organized from the viewpoint of information retrieval theory, this review addresses issues of chemical information representation, comparison and matching, and retrieval strategies. Additional topics include similarity and clustering, visualization, and molecular diversity. Trends in research and application are identified, and gaps in the…