Spatial ability is considered a major factor of intelligence and is increasingly important in times of digitization. This article explores the fostering of spatial ability through computer-aided design software. Different notions of spatial ability will be discussed, and, finally, a concept consisting of five aspects will be described. In addition, literature reviews on the connection between the use of computers and the fostering of spatial ability, as well as on the use of 3D printing technology in mathematics education, are given. Building on this, a case study is presented which examines the work of two middle-school students using computer-aided design software within a workshop at the University of Siegen. From the data material, basic possible actions within such software are derived. These are, based on theory, connected with the five aspects of the specific concept of spatial ability used. The results show various perspectives for the fostering of spatial ability with computer-aided design software.