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Zuhal Koc Apaydin; Meryem Kasak; Ozlem Karakaya; Hakan Ogutlu; Mustafa Ugurlu; Fiona McNicholas – Journal of Attention Disorders, 2025
Objective: This study aimed to investigate the relationship between Cognitive Disengagement Syndrome (CDS) symptoms in children/adolescents and their parents within the Turkish population, examining the association with co-occurring ADHD symptoms, peer/social relationships, and total difficulties. Method: The study included 229 parents aged 18 to…
Descriptors: Children, Adolescents, Parents, Symptoms (Individual Disorders)
Royston, R.; Oliver, C.; Howlin, P.; Dosse, A.; Armitage, P.; Moss, J.; Waite, J. – Journal of Autism and Developmental Disorders, 2020
Psychopathology is prevalent in Williams (WS), fragile X (FXS) and Prader-Willi (PWS) syndromes. However, little is known about the potential correlates of psychopathology in these groups. A questionnaire study was completed by 111 caregivers of individuals with WS (n = 35); FXS (n = 50) and PWS (n = 26). Mean age was 26 years (range 12-57 years);…
Descriptors: Psychopathology, Genetic Disorders, Correlation, Predictor Variables
Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Plourde, Vickie; Boivin, Michel; Forget-Dubois, Nadine; Brendgen, Mara; Vitaro, Frank; Marino, Cecilia; Tremblay, Richard T.; Dionne, Ginette – Journal of Child Psychology and Psychiatry, 2015
Background: The phenotypic and genetic associations between decoding skills and ADHD dimensions have been documented but less is known about the association with reading comprehension. The aim of the study is to document the phenotypic and genetic associations between reading comprehension and ADHD dimensions of inattention and…
Descriptors: Genetics, Correlation, Attention Deficit Hyperactivity Disorder, Kindergarten
Mick, Eric; McGough, James; Loo, Sandra; Doyle, Alysa E.; Wozniak, Janet; Wilens, Timothy E.; Smalley, Susan; McCracken, James; Biederman, Joseph; Faraone, Stephen V. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: A potentially useful tool for understanding the distribution and determinants of emotional dysregulation in children is a Child Behavior Checklist profile, comprising the Attention Problems, Anxious/Depressed, and Aggressive Behavior clinical subscales (CBCL-DP). The CBCL-DP indexes a heritable trait that increases susceptibility for…
Descriptors: Attention Deficit Hyperactivity Disorder, Check Lists, Aggression, Psychopathology
Mikolajewski, Amy J.; Allan, Nicholas P.; Hart, Sara A.; Lonigan, Christopher J.; Taylor, Jeanette – Journal of Abnormal Child Psychology, 2013
The co-occurrence of internalizing and externalizing disorders suggests that they may have common underlying vulnerability factors. Research has shown that negative affect is moderately positively correlated with both internalizing and externalizing disorders in children. The present study is the first to provide an examination of negative affect…
Descriptors: Behavior Disorders, Children, Genetics, Environmental Influences
Linker, Julie; Gillespie, Nathan A.; Maes, Hermine; Eaves, Lindon; Silberg, Judy L. – Suicide and Life-Threatening Behavior, 2012
The co-occurrence of suicidal ideation, depression, and conduct disturbance is likely explained in part by correlated genetic and environmental risk factors. Little is known about the specific nature of these associations. Structured interviews on 2,814 twins from the Virginia Twin Study of Adolescent Behavioral Development (VTSABD) and Young…
Descriptors: Twins, Intervention, Suicide, Risk
Pickles, Andrew; Hill, Jonathan; Breen, Gerome; Quinn, John; Abbott, Kate; Jones, Helen; Sharp, Helen – Journal of Child Psychology and Psychiatry, 2013
Background: The low expression polymorphism of the MAOA gene in interaction with adverse environments (G × E) is associated with antisocial behaviour disorders. These have their origins in early life, but it is not known whether MAOA G × E occurs in infants. We therefore examined whether MAOA G × E predicts infant anger proneness, a temperamental…
Descriptors: Antisocial Behavior, Behavior Disorders, Infants, Genetics
Lahey, Benjamin B.; Waldman, Irwin D. – Journal of Child Psychology and Psychiatry, 2012
Background: A better understanding of the nature and etiology of conduct disorder (CD) can inform nosology and vice versa. We posit that any prevalent form of psychopathology, including CD, can be best understood if it is studied in the context of other correlated forms of child and adolescent psychopathology using formal models to guide inquiry.…
Descriptors: Evidence, Twins, Causal Models, Psychopathology
Martel, Michelle M.; Nikolas, Molly; Jernigan, Katherine; Friderici, Karen; Waldman, Irwin; Nigg, Joel T. – Journal of Abnormal Child Psychology, 2011
Attention-Deficit/Hyperactivity Disorder (ADHD) is a prime candidate for exploration of gene-by-environment interaction (i.e., G x E), particularly in relation to dopamine system genes, due to strong evidence that dopamine systems are dysregulated in the disorder. Using a G x E design, we examined whether the "DRD4" promoter 120-bp tandem repeat…
Descriptors: Conflict, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorders, Child Rearing
Jucksch, Viola; Salbach-Andrae, Harriet; Lenz, Klaus; Goth, Kirstin; Dopfner, Manfred; Poustka, Fritz; Freitag, Christine M.; Lehmkuhl, Gerd; Lehmkuhl, Ulrike; Holtmann, Martin – Journal of Child Psychology and Psychiatry, 2011
Background: Recently, a highly heritable behavioral phenotype of simultaneous deviance on the Anxious/Depressed, Attention Problems, and Aggressive Behavior syndrome scales has been identified on the Child Behavior Checklist (CBCL-Dysregulation Profile, CBCL-DP). This study aims to investigate psychosocial adversity and impairment of the CBCL-DP.…
Descriptors: Control Groups, Check Lists, Behavior Problems, Aggression
Glover, Vivette – Journal of Child Psychology and Psychiatry, 2011
If a mother is stressed or anxious while pregnant her child is more likely to show a range of symptoms such as those of attention deficit hyperactivity disorder, conduct disorder, aggression or anxiety. While there remains some debate about what proportion of these effects are due to the prenatal or the postnatal environment, and the role of…
Descriptors: Attention Deficit Hyperactivity Disorder, Psychopathology, Genetics, Depression (Psychology)
Malone, Stephen M.; McGue, Matt; Iacono, William G. – Journal of Child Psychology and Psychiatry, 2010
Background: The maximum number of alcoholic drinks consumed in a single 24-hr period is an alcoholism-related phenotype with both face and empirical validity. It has been associated with severity of withdrawal symptoms and sensitivity to alcohol, genes implicated in alcohol metabolism, and amplitude of a measure of brain activity associated with…
Descriptors: Mental Health, Pregnancy, Adolescents, Mothers
Subbarao, Anjali; Rhee, Soo Hyun; Young, Susan E.; Ehringer, Marissa A.; Corley, Robin P.; Hewitt, John K. – Journal of Abnormal Child Psychology, 2008
The evidence for common genetic and environmental influences on conduct disorder (CD) and major depressive disorder (MDD) in adolescents was examined. A sample of 570 monozygotic twin pairs, 592 dizygotic twin pairs, and 426 non-twin siblings, aged 12-18 years, was recruited from the Colorado Twin Registry. For the past year data, there was a…
Descriptors: Twins, Genetics, Environmental Influences, Depression (Psychology)
Sterba, Sonya K.; Copeland, William; Egger, Helen L.; Costello, E. Jane; Erkanli, Alaattin; Angold, Adrian – Journal of Child Psychology and Psychiatry, 2010
Background: The differentiation hypothesis posits that the underlying liability distribution for psychopathology is of low dimensionality in young children, inflating diagnostic comorbidity rates, but increases in dimensionality with age as latent syndromes become less correlated. This hypothesis has not been adequately tested with longitudinal…
Descriptors: Attention Deficit Hyperactivity Disorder, Psychopathology, Depression (Psychology), Separation Anxiety
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