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Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Pennings, Jacquelyn; McFarlane, Judith M.; Paulson, Rene; Fredland, Nina; Binder, Brenda; Koci, Anne; Montalvo, Nora – Journal of Applied Research on Children, 2015
Objective: To design and test a rapid assessment tool for predicting dysfunctional behavior of children who live in homes where their mother reports recent physical or sexual partner abuse. Methods: A cohort analysis was completed. 300 abused mothers accessing services for partner abuse were interviewed to determine risk factors for dysfunctional…
Descriptors: Prediction, Behavior Problems, Behavior Disorders, Mother Attitudes
Ditchburn, K. Marie; Sellman, J. Douglas – Journal of Child & Adolescent Substance Abuse, 2013
Three main aims of this study were to ascertain the prevalence rate of smoking among adolescent psychiatric outpatients; estimate smokers' degree of nicotine dependence; and investigate the relationship between smoking and common mental health disorders. Face-to-face interviews were conducted on 93 patients ages 13-18 presenting to an adolescent…
Descriptors: Foreign Countries, Smoking, Attention Deficit Hyperactivity Disorder, Mental Health
Bridgett, David J.; Valentino, Kristin; Hayden, Lisa C. – Child Psychiatry and Human Development, 2012
The current study examined temperament characteristics as risk factors for restraint and seclusion (R/S) events in psychiatrically hospitalized youth, extending work that has sought to identify R/S risk factors and research examining temperament-behavior problem associations that has largely relied upon community samples. It was anticipated that…
Descriptors: Risk, Behavior Disorders, Behavior Problems, Personality Traits
White, Stuart F.; Brislin, Sarah; Sinclair, Stephen; Fowler, Katherine A.; Pope, Kayla; Blair, R. James R. – Journal of Child Psychology and Psychiatry, 2013
Background: The presence of a large cavum septum pellucidum (CSP) has been previously associated with antisocial behavior/psychopathic traits in an adult community sample. Aims: The current study investigated the relationship between a large CSP and symptom severity in disruptive behavior disorders (DBD; conduct disorder and oppositional defiant…
Descriptors: Antisocial Behavior, Psychopathology, Personality Traits, Correlation
Jucksch, Viola; Salbach-Andrae, Harriet; Lenz, Klaus; Goth, Kirstin; Dopfner, Manfred; Poustka, Fritz; Freitag, Christine M.; Lehmkuhl, Gerd; Lehmkuhl, Ulrike; Holtmann, Martin – Journal of Child Psychology and Psychiatry, 2011
Background: Recently, a highly heritable behavioral phenotype of simultaneous deviance on the Anxious/Depressed, Attention Problems, and Aggressive Behavior syndrome scales has been identified on the Child Behavior Checklist (CBCL-Dysregulation Profile, CBCL-DP). This study aims to investigate psychosocial adversity and impairment of the CBCL-DP.…
Descriptors: Control Groups, Check Lists, Behavior Problems, Aggression
Cavanagh, James F.; Grundler, Theo O. J.; Frank, Michael J.; Allen, John J. B. – Neuropsychologia, 2010
Larger error-related negativities (ERNs) have been consistently found in obsessive-compulsive disorder (OCD) patients, and are thought to reflect the activities of a hyperactive cortico-striatal circuit during action monitoring. We previously observed that obsessive-compulsive (OC) symptomatic students (non-patients) have larger ERNs during errors…
Descriptors: Competition, Patients, Memory, Anatomy
Draganski, Bogdan; Martino, Davide; Cavanna, Andrea E.; Hutton, Chloe; Orth, Michael; Robertson, Mary M.; Critchley, Hugo D.; Frackowiak, Richard S. – Brain, 2010
Tourette syndrome is a childhood-onset neuropsychiatric disorder with a high prevalence of attention deficit hyperactivity and obsessive-compulsive disorder co-morbidities. Structural changes have been found in frontal cortex and striatum in children and adolescents. A limited number of morphometric studies in Tourette syndrome persisting into…
Descriptors: Attention Deficit Hyperactivity Disorder, Integrity, Patients, Brain
Tenneij, Nienke; Didden, Robert; Veltkamp, Eline; Koot, Hans M. – Journal of Mental Health Research in Intellectual Disabilities, 2009
In this study, psychometric properties of the Health of the Nation Outcome scales (HoNOS) and Health of the Nation Outcome Scales for People with Learning Disabilities (HoNOS-LD) were investigated in a sample (n = 79) of (young) adults with mild to borderline intellectual disability (ID) and severe behavior and mental health problems who were…
Descriptors: Mild Mental Retardation, Young Adults, Predictive Validity, Behavior Disorders
Kollins, Scott H. – Journal of Attention Disorders, 2008
Objective: This review explores the relationship between ADHD and substance use disorder (SUD), factors that determine the abuse potential of psychostimulants, and strategies for identifying and treating at-risk ADHD patients. Method: This study uses a Medline review of literature. Results: Psychostimulants, such as methylphenidate and…
Descriptors: Stimulants, Attention Deficit Disorders, Patients, Hyperactivity
Price, James H.; Sidani, Jaime E.; Price, Joy A. – Journal of the American Academy of Child and Adolescent Psychiatry, 2007
Objective: This national study examined the practices and perceptions of smoking cessation activities among child and adolescent psychiatrists. Method: A random sample of child and adolescent psychiatrists was identified from the membership list of the American Academy of Child and Adolescent Psychiatry and was mailed a valid and reliable 34-item…
Descriptors: Psychiatry, Patients, Schizophrenia, Hyperactivity
Drotar, Dennis; Greenley, Rachel Neff; Demeter, Christine A.; McNamara, Nora K.; Stansbrey, Robert J.; Calabrese, Joseph R.; Stange, Jonathan; Vijay, Priya; Findling, Robert L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: The objective of this study was to describe the prevalence and correlates of adherence to divalproex sodium (DVPX) and lithium carbonate (Li) combination treatment during the initial stabilization treatment phase. Method: Adherence to Li/DVPX combination therapy was measured by the presence or absence of minimum serum concentrations of…
Descriptors: Medical Evaluation, Outcomes of Treatment, Patients, Drug Therapy
Measuring Depression at the End of Life: Is the Hamilton Depression Rating Scale a Valid Instrument?
Olden, Megan; Rosenfeld, Barry; Pessin, Hayley; Breitbart, William – Assessment, 2009
Depression at the end of life is a common mental health issue with serious implications for quality of life and decision making. This study investigated the reliability and validity of one of the most frequently used measures of depression, the Hamilton Depression Rating Scale (HAM-D) in 422 patients with terminal cancer admitted to a palliative…
Descriptors: Quality of Life, Validity, Suicide, Rating Scales
Wilens, Timothy E.; Gignac, Martin; Swezey, Allison; Monuteaux, Michael C.; Biederman, Joseph – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: Little is known about the risks and characteristics of attention-deficit/hyperactivity disorder (ADHD) patients who misuse or divert their stimulant medications. As part of a 10-year longitudinal study of youths with ADHD, the authors evaluated medication diversion or misuse at the last follow-up period. Method: Structured psychiatric…
Descriptors: Patients, Adolescents, Young Adults, Siblings
Recklitis, Christopher J.; Noam, Gil G. – Child Psychiatry and Human Development, 2004
Objective: This study examined the relationship between ego development and psychological defenses to aggressive behavior in a group of psychiatrically hospitalized adolescents. Method: Subjects were 245 adolescents ages 12-16, who were assessed for aggressive behaviors, assaultive incidents, ego development and defenses. Results: Aggressive…
Descriptors: Adolescents, Patients, Aggression, Defense Mechanisms
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