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Direct linkPedder, Hugo; Boucher, Martin; Dias, Sofia; Bennetts, Margherita; Welton, Nicky J. – Research Synthesis Methods, 2020
Time-course model-based network meta-analysis (MBNMA) has been proposed as a framework to combine treatment comparisons from a network of randomized controlled trials reporting outcomes at multiple time-points. This can explain heterogeneity/inconsistency that arises by pooling studies with different follow-up times and allow inclusion of studies…
Descriptors: Simulation, Randomized Controlled Trials, Meta Analysis, Comparative Analysis
Saluja, Ronak; Cheng, Sierra; delos Santos, Keemo Althea; Chan, Kelvin K. W. – Research Synthesis Methods, 2019
Objective: Various statistical methods have been developed to estimate hazard ratios (HRs) from published Kaplan-Meier (KM) curves for the purpose of performing meta-analyses. The objective of this study was to determine the reliability, accuracy, and precision of four commonly used methods by Guyot, Williamson, Parmar, and Hoyle and Henley.…
Descriptors: Meta Analysis, Reliability, Accuracy, Randomized Controlled Trials
