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Direct linkSaima, Sohei; Ihara, Hiroshi; Ogata, Hiroyuki; Gito, Masao; Murakami, Nobuyuki; Oto, Yuji; Ishii, Atsushi; Takahashi, Asami; Nagai, Toshiro – American Journal on Intellectual and Developmental Disabilities, 2022
The relationship between sensory processing and ASD-like and associated behaviors in patients with Prader-Willi Syndrome (PWS) remains relatively unexplored. Examining this relationship, 51 adults with PWS were administered the Pervasive Developmental Disorders Autism Society Japan Rating Scale (PARS), Short Sensory Profile (SSP-J), Food-Related…
Descriptors: Sensory Experience, Autism, Pervasive Developmental Disorders, Behavior Problems
Markiewicz, Katarzyna; Kaczmarek, Bozydar L. J.; Filipiak, Sara – Journal of Autism and Developmental Disorders, 2021
The study aimed to identify the mediating role of emotional intelligence and social competences in the relationship between gender and broad autism phenotype (BAP) as well as between age and BAP. It comprised 85 parents of children with ASD. They completed the questionnaires of Autism-Spectrum Quotient, social competences, and emotional…
Descriptors: Emotional Intelligence, Interpersonal Competence, Correlation, Gender Differences
Shindler, A. E.; Hill-Yardin, E. L.; Petrovski, S.; Bishop, N.; Franks, A. E. – Journal of Autism and Developmental Disorders, 2020
This study investigated genetic biomarkers for gastrointestinal dysfunction symptoms in order to provide further information on the genetic risk for GI dysfunction associated with autism. The single nucleotide polymorphisms of sixty participants with autism and/or gastrointestinal dysfunction were analyzed. The autism group had a moderate…
Descriptors: Genetics, Symptoms (Individual Disorders), Physiology, Risk
Condy, Emma E.; Factor, Reina S.; Swain, Deanna M.; Strege, Marlene V.; Scarpa, Angela – Journal of Autism and Developmental Disorders, 2019
Respiratory sinus arrhythmia (RSA) is proposed to index cognitive and behavioral inflexibility. Broad autism phenotype (BAP) traits are prevalent in family members of children with autism spectrum disorder (ASD). The study investigated whether RSA and BAP traits in mothers of typically developing (TD) children and mothers of children with ASD…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Mothers
Cord and Early Childhood Plasma Adiponectin Levels and Autism Risk: A Prospective Birth Cohort Study
Raghavan, Ramkripa; Fallin, M. Daniele; Hong, Xiumei; Wang, Guoying; Ji, Yuelong; Stuart, Elizabeth A.; Paige, David; Wang, Xiaobin – Journal of Autism and Developmental Disorders, 2019
Emerging research suggests that adiponectin, a cytokine produced by adipose tissue, may be implicated in ASD. In this prospective birth cohort study (n = 847), we assessed the association between cord, early childhood plasma adiponectin and the risk of developing ASD. ASD was defined based on ICD codes of physician diagnosis. Cord adiponectin…
Descriptors: Autism, Pervasive Developmental Disorders, Risk, Physiology
Kim, Bora; Ha, Mina; Kim, Young Shin; Koh, Yun-Joo; Dong, Shan; Kwon, Ho-Jang; Kim, Young-Suk; Lim, Myung-Ho; Paik, Ki-Chung; Yoo, Seung-Jin; Kim, Hosanna; Hong, Patricia S.; Sanders, Stephan J.; Leventhal, Bennett L. – Autism: The International Journal of Research and Practice, 2021
Genetics, environment, and their interactions impact autism spectrum disorder etiology. Smoking is a suspected autism spectrum disorder risk factor due to biological plausibility and high prevalence. Using two large epidemiological samples, we examined whether autism spectrum disorder was associated with prenatal paternal smoking in a Discovery…
Descriptors: Prenatal Influences, Pregnancy, Genetics, Environmental Influences
Hu, Valerie W.; Hong, Yi; Xu, Minyi; Shu, Henry T. – Autism: The International Journal of Research and Practice, 2021
Although differences in DNA methylation have been associated with both syndromic and idiopathic autism, differential methylation has not been examined previously with respect to sex differences. The goals of this study were to (1) identify differences in the DNA methylation profiles of lymphoblastoid cell lines derived from a subgroup of severely…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Correlation
Kurtz-Nelson, Evangeline C.; Tham, See Wan; Ahlers, Kaitlyn; Cho, Daniel; Wallace, Arianne S.; Eichler, Evan E.; Bernier, Raphael A.; Earl, Rachel K. – Journal of Autism and Developmental Disorders, 2021
Self-injurious behaviors (SIB) are elevated in autism spectrum disorder (ASD) and related genetic disorders, but the genetic and biological mechanisms that contribute to SIB in ASD are poorly understood. This study examined rates and predictors of SIB in 112 individuals with disruptive mutations to ASD-risk genes. Current SIB were reported in 30%…
Descriptors: Self Destructive Behavior, Injuries, Autism, Pervasive Developmental Disorders
Sabatino DiCriscio, Antoinette; Troiani, Vanessa – Journal of Autism and Developmental Disorders, 2018
Atypical visual perception has increasingly been described in individuals with autism spectrum disorders (ASD) and linked to quantitative, autism-like features that are present in children and adults without ASD. We investigated whether individual differences in visual processing skills were related to quantitative measures of autism traits in a…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Visual Perception
Qualls, Lydia R.; Hartmann, Kathrin; Paulson, James F. – Journal of Autism and Developmental Disorders, 2018
Individuals with higher levels of the broad autism phenotype (BAP) have some symptoms of autism spectrum disorder (ASD). Like individuals with ASD, people with higher-BAP may have fewer sexual experiences and may experience more same-sex attraction. This study measured BAP traits, sexual experiences, and sexual orientation in typically developing…
Descriptors: Sexuality, Genetics, Autism, Pervasive Developmental Disorders
Ali, Yamna; Anderson, Laura N.; Smile, Sharon; Chen, Yang; Borkhoff, Cornelia M.; Koroshegyi, Christine; Lebovic, Gerald; Parkin, Patricia C.; Birken, Catherine S.; Szatmari, Peter; Maguire, Jonathon L. – Autism: The International Journal of Research and Practice, 2019
Several studies have suggested an association between vitamin D in childhood and autism spectrum disorder. No prospective studies have evaluated whether lower vitamin D levels precede ASD diagnoses -- a necessary condition for causality. The objective of this study was to prospectively evaluate whether vitamin D serum levels in early childhood was…
Descriptors: Autism, Pervasive Developmental Disorders, Nutrition, Preschool Children
Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Roberts, Andrea L.; Lyall, Kristen; Weisskopf, Marc G. – Journal of Autism and Developmental Disorders, 2017
Maternal experience of childhood abuse has been associated with offspring autism. To explore whether familial tendency towards autistic traits--presumably related to genetic predisposition--accounts for this association, we examined whether women who experienced childhood abuse were more likely to select mates with high levels of autistic traits,…
Descriptors: Mothers, Child Abuse, Parent Influence, Autism
Krasileva, Kate E.; Sanders, Stephan J.; Bal, Vanessa Hus – Journal of Autism and Developmental Disorders, 2017
This study assessed the utility of a brief assessment (the Peabody Picture Vocabulary Test-4th Edition; PPVT4) as a proxy for verbal IQ (VIQ) in large-scale studies of autism spectrum disorder (ASD). In a sample of 2,420 proband with ASD, PPVT4:IQ correlations were strong. PPVT4 scores were, on average, 5.46 points higher than VIQ; 79% of children…
Descriptors: Autism, Pervasive Developmental Disorders, Intelligence Tests, Verbal Ability
Osório, Ana Alexandra Caldas; do Egito, Júlia Horta Tabosa; Martins, Gabriela Carneiro; Kim, Chong Ae; Honjo, Rachel Sayuri; Sampaio, Adriana da Conceição Soares; Mesquita, Ana Raquel Marcelino; Macedo, Elizeu Coutinho; Boggio, Paulo Sérgio; Teixeira, Maria Cristina Triguero Veloz – International Journal of Developmental Disabilities, 2019
Objective: Fetal testosterone (fT) has organizational effects on the developing human nervous system and can be reliably estimated by the ratio between the length of the second and fourth digits -- 2D:4D. Previous studies reported altered patterns of fT in some developmental disabilities (e.g. ASD) relative to typically developing individuals…
Descriptors: Correlation, Prosocial Behavior, Prenatal Influences, Males
