Background: The aim was to explore the executive function profile of a group of Mexican people with Down syndrome (DS) aged 12-30 years during the COVID-19 pandemic. Aim: To analyse the relationships between mental, chronological age and eight domains of executive function. Method: Participants were 42 people with DS with a chronological age (CA) of 12-30 years and a mean nonverbal mental age (MA) of 7 years. MA was evaluated with Raven's Progressive Matrices test and executive function with the Behaviour Rating Inventory of Executive Function (BRIEF-2); both were administered online. Results: The Monitor, Emotional Control, Initiative, and Organisation of Materials scales showed strengths, while Working Memory, Plan/Organise, Shift, and Inhibit scales showed weaknesses. CA correlated negatively with seven of the eight executive domains. Chronologically older participants showed less impairment in skills such as inhibition, emotional control, working memory, and monitoring. Nonverbal MA correlated negatively with two domains: emotional control and monitoring. Conclusion: Participants' executive profile during the COVID-19 pandemic was consistent with that reported in studies prior to the pandemic.