Despite the growing numbers of Muslims in the United States, there is a scarcity of research dealing with mental health practitioners working with Muslim families. This lack of research may leave clinicians unprepared to adequately help Muslim patients and families faced with discrimination and misunderstanding, which may inadvertently lead to the perpetuation of biases in therapy. Therefore, the purpose of this paper is (a) to provide mental health practitioners with foundational information regarding the Islamic faith and the values of the traditional Muslim families and (b) to provide culturally sensitive guidelines for clinical practice.