Understanding the details of how scientific breakthroughs and discoveries emerge from prior work, knowledge, and collaboration is fundamental to science history. Traditional methods of collecting such relevant information and transforming it into rich narratives have existed since the inception of the scientific method. These typically involve…

This study aimed to enhance students' experimental skills and laboratory techniques in cell and molecular biology. A trifold intervention involving a Gene Screen Worksheet, a Gene Screen Flowchart, and a laboratory manual were used, along with a mixed methods approach to data collection. The trifold intervention was grounded in constructivism,…

There have been many attempts to address the deficits in traditional teaching methods for decades Multiple studies have been done on the Common Knowledge Construction Model (CKCM) and the results of each study has shown an improvement. The addition of relational conceptual change has added much needed improvement in teaching science. This study,…

There is a consistent concern for students' success in undergraduate introductory cell biology as this foundational course may impact their persistence towards earning a degree in the health sciences. Institutions need to consider the delivery method of instruction and the potential impacts on student success and enrollment. For five years, the…

The purpose of this study is to assess the effectiveness of a mandatory online supplemental instruction program in an introductory cell and molecular biology course at a community college in Northern Nevada. To accomplish this, the study focused on the dependent variable of course GPA, and the issuance rate of "D" or "F" letter…

While zinc (Zn[superscript 2+]) is a vital ion for cell function and human health, we are still learning about how Zn[superscript 2+] concentration and localization is regulated and the role that Zn[superscript 2+] fluctuations may play in regulating cell signaling and cell fate. Here, we use fluorescent tools to study the interaction between…

Lacking in educational research are the positive narratives of Black male students and their science classroom learning experiences, as told through the voices of Black male science students. This study highlighted the normative scientific practices found in "A Framework for K-12 Science Education" that four Black male science students…

Despite the number of university students who take courses in multiple science disciplines, little is known about how they perceive common concepts from different disciplinary perspectives and to what extent they recognize connections among their courses. This dissertation explores students' perceptions of their chemistry and biology courses…

Transition metals play an important role in many biological processes, however, they are also toxic at high concentrations. Therefore, the uptake and efflux of these metals must be tightly regulated by the cell. Bacteria have evolved a variety of pathways and regulatory systems to monitor the presence and concentration of metals in the cellular…

Part I. Pleural fibrosis, a non-malignant, asbestos-related respiratory disease characterized by excessive collagen deposition, is progressive, debilitating, and potentially fatal. Disease severity may be influenced by the type of asbestos fiber inhaled, with Libby amphibole (LA) a seemingly more potent mediator of pleural fibrosis than chrysotile…

One of the great challenges to teachers both historically and contemporarily is to facilitate a classroom as a "group" of students, while concurrently attending to each "individual" student. As the profession becomes increasingly aware and sensitive to student (dis)abilities, academic giftedness, pressures of athletics and…

Traditionally, cytotechnology (CT) students have been trained by using light microscopy (LM) and glass slides. However, this method of training has some drawbacks. Several other educational programs with similar issues have incorporated virtual microscopy (VM) in their curricula. In VM, the specimens on glass slides are converted into virtual…

The primary objective of this project was to learn what effect a computer program would have on academic achievement and attitude toward science of college students enrolled in a biology class for non-science majors. It became apparent that the instructor also had an effect on attitudes toward science. The researcher designed a computer program,…

RNA modification, RNA interference, and RNA repair are important events in the cell. This thesis presents three projects related to these three fields. By using both biochemical and structural methods, we characterized enzymatic activities of pseudouridine synthase TruD, solved the structure of "A. aeolicus" GidA, and reconstituted a novel…

Chapter 1: The role of cell division in protein expression is important to understand in order to guide the development of better nonviral gene delivery materials that can transport DNA to the nucleus with high efficiency for a variety of cell types, particularly when nondividing cells are targets of gene therapy. We evaluated the relationship…