Transposable elements (TEs) have been implicated in autism spectrum disorder (ASD). However, our understanding of their roles is far from complete. Herein, we explored de novo TE insertions (dnTEIs) and de novo variants (DNVs) across the genomes of dizygotic twins with ASD and their parents. The neuronal regulatory elements had a tendency to…

Mathematics provides us with tools to capture and explain phenomena in everyday biology, even at the nanoscale. The most regularly applied technique to biology is differential equations. In this article, we seek to present how differential equation models of biological phenomena, particularly the flow through ion channels, can be used to motivate…

We developed a fluorescence microscopy lesson geared towards high school students. Our goals included demonstrating how fluorescence microscopy works and illustrating the localisation of key cellular structures/organelles in the model organism, budding yeast. A trained student teacher/researcher on our team took the microscopy images and…

Virtual Reality (VR) involves the coupling of visual communication hardware and software. The technology is capable of offering transformative educational practice and is increasingly being adopted within the biochemistry domain to better understand complex biochemical processes. This article documents a pilot study for the efficacy of VR in…

It has been shown that many people do not understand how scientific knowledge is built and accepted, even after scientific education. One way to deal with this problem is through teaching about the Nature of Science (NOS). NOS can be understood as a pedagogical construct aiming to foster the understanding of the main characteristics of scientific…

Learning media is a tool that makes it easier for educators to convey material to students effectively and efficiently to improve the quality of learning. Biology subjects in the essential enzymes and cell metabolism competencies require precision and accuracy, so appropriate learning media are needed. Booklets are a medium that can make it easier…

Systematic reviews (SRs) of preclinical studies are marked with poor methodological quality. In vitro studies lack assessment tools to improve the quality of preclinical research. This methodological study aimed to identify, collect, and analyze SRs based on cell culture studies to highlight the current appraisal tools utilized to support the…

Explaining biological phenomena requires understanding how different processes function and describing interactions between components at various levels of organization over time and space in biological systems. This is a desired competency yet is a complicated and often challenging task for undergraduate biology students. Therefore, we need a…

When students use metacognition, they can more effectively problem solve on their own and in groups. Most metacognition studies have focused on individual learners while a few studies have begun to explore the metacognition learners use in social settings. Little is known about the comparison between how an individual student may use metacognition…

Biological interactions and associations underlie life's processes at every level of organization. Here, we present a classroom activity that allows students to visualize and understand the connections within almost any biological system, from cell functions to ecological relationships. We recommend that instructors implement this activity to…

The central dogma of molecular biology describes the transfer of genetic information from nucleic acids to proteins and stipulates that the system cannot work in the reverse direction. As a fundamental principle in biology, the dogma is as influential as it is controversial. Some commentators have debated the central dogma's empirical accuracy…

This study is the first phase of an on-going study. It shows the first implementation of a teaching-learning sequence designed to facilitate the understanding of the notion of a living being in initial teacher training using modelling approaches. It aims to analyse the knowledge progression of the participants (N=51) through a retrospective…

Heart muscle cells, or cardiomyocytes, exhibit intrinsic contractility in vitro. We found that commercially-available mammalian cardiomyocytes serve as an excellent model system for studying the cytoskeleton and cellular contractility, fundamental topics in undergraduate cell and molecular biology courses. Embryonic rat cardiomyocytes were plated…

Understanding the details of how scientific breakthroughs and discoveries emerge from prior work, knowledge, and collaboration is fundamental to science history. Traditional methods of collecting such relevant information and transforming it into rich narratives have existed since the inception of the scientific method. These typically involve…

To reduce the cost of educational materials needed by students, we generated a no-cost open educational resources (OER) textbook for an undergraduate level cell biology course. Cell biology is part of the curriculum in various undergraduate degrees for science, technology, engineering, and math majors, therefore generation of OER targets a large…