Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

Interrupted time series (ITS) studies are frequently used to examine the impact of population-level interventions or exposures. Systematic reviews with meta-analyses including ITS designs may inform public health and policy decision-making. Re-analysis of ITS may be required for inclusion in meta-analysis. While publications of ITS rarely provide…

The purpose of this study was to compare 12 commonly-used nonoverlap methods with each other and with the results of visual analysis. Data were obtained from 25 studies focused on embedded instruction and schema-based instruction and included a total of 101 graphs. Treatment effect estimates using 12 nonoverlap methods were calculated for each…

Social network data often contain missing values because of the sensitive nature of the information collected and the dependency among the network actors. As a response, network imputation methods including simple ones constructed from network structural characteristics and more complicated model-based ones have been developed. Although past…

While computational chemistry continues to play a growing role in chemical research, issues with access and the timing of when these tools are introduced to chemistry students remain as barriers to wider interest and use. The accessibility of free software for chemical modeling has increased in recent years, promoting the inclusion of…

For the least-squares analysis of data having multiple uncertain variables, the generally accepted best solution comes from minimizing the sum of weighted squared residuals over all uncertain variables, with, for example, weights in x[subscript i] taken as inversely proportional to the variance [delta][subscript xi][superscript 2]. A complication…

Augmented Graph Grammars are a graph-based rule formalism that supports rich relational structures. They can be used to represent complex social networks, chemical structures, and student-produced argument diagrams for automated analysis or grading. In prior work we have shown that Evolutionary Computation (EC) can be applied to induce…

Graph data such as argument diagrams has become increasingly common in EDM. Augmented Graph Grammars are a robust rule formalism for graphs. Prior research has shown that hand-authored graph grammars can be used to automatically grade student-produced argument diagrams. But hand-authored rules can be time consuming and expensive to produce, and…

Previous research has demonstrated how young children can identify the signal in data. In this exploratory study we considered how they might also express meanings for noise when creating computational models using recent developments in software tools. We conducted extended clinical interviews with four groups of 11-year-olds and analysed the…

A "Framework for K-12 Science Education" identified eight practices as "essential elements of the K-12 science and engineering curriculum" (NRC 2012, p. 49). Most of the practices, such as Developing and Using Models, Planning and Carrying Out Investigations, and Analyzing and Interpreting Data, are well known among science…

In this article a continuous-time stochastic model (the Ornstein-Uhlenbeck process) is presented to model the perpetually altering states of the core affect, which is a 2-dimensional concept underlying all our affective experiences. The process model that we propose can account for the temporal changes in core affect on the latent level. The key…

Every student should understand and use all concepts and skills from the previous grade levels. The standard is designed so that new learning builds on preceding skills. Communications, Problem-solving, Reasoning & Proof, Connections, and Representation are the process standards that are embedded throughout the teaching and learning of all…

Every student should understand and use all concepts and skills from the previous grade levels. The standard is designed so that new learning builds on preceding skills. Communications, Problem-solving, Reasoning & Proof, Connections, and Representation are the process standards that are embedded throughout the teaching and learning of all…

The 10th International Conference on Educational Data Mining (EDM 2017) is held under the auspices of the International Educational Data Mining Society at the Optics Velley Kingdom Plaza Hotel, Wuhan, Hubei Province, in China. This years conference features two invited talks by: Dr. Jie Tang, Associate Professor with the Department of Computer…

This generic science education study demonstrates the contrast of findings obtained through analyzing all the raw data as opposed to removing various combinations of identified potential outliers provided through the application of six diagnostic procedures. Outliers are defined as extreme data points with large residuals. It is argued that an…