Meta-analysis allows researchers to combine evidence from multiple studies, making it a powerful tool for synthesizing information on the safety profiles of new medical interventions. There is a critical need to identify subgroups at high risk of experiencing treatment-related toxicities. However, this remains quite challenging from a statistical…

Research in Educational Data Mining could benefit from greater efforts to ensure that models yield reliable, valid, and interpretable parameter estimates. These efforts have especially been lacking for individualized student-parameter models. We collected two datasets from a sizable student population with excellent "depth" -- that is,…

Microarray is a high throughput technology to measure the gene expression. Analysis of microarray data brings many interesting and challenging problems. This thesis consists three studies related to microarray data. First, we propose a Bayesian model for microarray data and use Bayes Factors to identify differentially expressed genes. Second, we…