This protocol guides the review of research that informs the What Works Clearinghouse (WWC) intervention reports in the Developmental Education topic area. The protocol is used in conjunction with the "WWC Procedures and Standards Handbooks (version 4.0)." Not all students enrolled in college are prepared to do college-level work in all subjects. Anticipating this need, most colleges have established processes that are intended to identify students who are not prepared to do college-level work. For example, colleges may establish a threshold score on an entrance test, such as the SAT or ACT, and/or require that students take a placement test. Students who are not prepared for college-level work would then be placed into developmental (or remedial) education, which involves taking courses that are intended to help students succeed. These courses are usually offered on a non-credit basis; therefore, they do not count toward graduation requirements. Alternatively, students who are not prepared for college-level work may be offered corequisite remediation, which involves coupling mainstream, credit-bearing college classes with mandatory non-credit remedial support. WWC reviews in this topic area focus on developmental education interventions that help incoming and current postsecondary students prepare for college-level coursework, increase academic achievement, improve course completion rates, improve labor market outcomes, and increase degree or certification attainment.