ERIC Number: EJ1422552
Record Type: Journal
Publication Date: 2023-Mar
Pages: 15
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-2195-7177
EISSN: EISSN-2195-7185
Available Date: N/A
Amygdala Volumes in Autism Spectrum Disorders: Meta-Analysis of Magnetic Resonance Imaging Studies
Marija Kovacevic; Ivana Zivanovic Macuzic; Jovana Milosavljevic; Tanja Lukovic; Dejan Aleksic; Jagoda Gavrilovic; Milos Milosavljevic; Slobodan Jankovic; Ana Pejcic
Review Journal of Autism and Developmental Disorders, v10 n1 p169-183 2023
We conducted meta-analysis in order to determine if there are significant differences in left and right amygdala volume in individuals with autism spectrum disorders (ASD) compared to a control group. Twenty-three studies fulfilled inclusion criteria for our study. Right amygdala volume was significantly larger in ASD patients compared to controls (Hedges' g 0.44; 95% CI 0.04-0.83; Z = 2.26; p = 0.024), while there was no significant difference in left amygdala volume between ASD patients and controls (Hedges' g 0.44; 95% CI - 0.10-0.98; Z = 1.67; p = 0.095). However, between-study heterogeneity was significant so there is an unequivocal need for new uniform magnetic resonance imaging (MRI) studies to get a more precise answer to the question of whether there is a difference in amygdala volume between ASD patients and controls.
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Publication Type: Journal Articles; Information Analyses
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
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Author Affiliations: N/A