Multifaceted interventions are interventions which target two or more individual or environmental characteristics in different domains. For example, many factors affect the outcome of integrated, competitive employment in the community for people with disabilities. Among those factors, there are points of intervention related to the individual (e.g., work experience, social skills, level of support needs, education/training), the employer or workplace (e.g., disability awareness, provision of accommodations, accessibility), and the community (e.g., access to transport, proximity to workplace). This Campbell systematic review and meta-analysis examines the impact of multifaceted interventions on community participation outcomes for adults with disabilities, and aims to find effective components of the interventions. The review summarizes the findings from 15 reports of multifaceted interventions in five countries.