Inhibition and Working Memory (WM) are crucial predictors of everyday life autonomies in people with Down Syndrome (DS). We aimed to investigate the possible relationship between different levels of autonomy, inhibitory sub-components and WM in people with DS. Twenty-two adolescents and adults with DS were enrolled in the study and were assessed…

Background: At least half of children and adults with Down syndrome have a major mental health concern during their life but few studies ask people with Down syndrome directly about their experience. We used a co-research model to explore anxiety, stress, and coping in adults with Down syndrome. Methods: Our group of researchers and adults with…

Purpose: Adolescents and adults with Down syndrome are noted to display symptoms and behaviors consistent with a diagnosis of Obsessive Compulsive Disorder. While evidenced-based interventions, including psychopharmacology and therapeutic interventions including exposure and response prevention, exist and effectively treat obsessive-compulsive…

Background: Sedentary behaviour (SB) among adults with Down syndrome (DS) may differ based on personal or environmental factors. Objective: Investigate differences in SB levels and patterns of adults with DS based on sex, age, and residence-type across weekdays and weekends. Methods: Thirty-four adults with DS (15 men; 37 ± 12 years) underwent…

Introduction: The VO[subscript 2] max test is the gold standard measure for aerobic fitness. A standardised treadmill protocol was developed years ago for individuals with Down syndrome but with variations in terms of starting speed, load increases and time spent at each stage. However, we realised that the most widely used protocol for adults…

Background: The evidence on the effect of age on the receptive and expressive language skills of individuals with Down syndrome is inconclusive. Recent research highlights the relevance of having tools to detect age-related changes in language skills. Method: Data were collected on 45 adults with Down syndrome. All were assessed with the Peabody…

Background: Chewing difficulty, poor oral health, inadequate and imbalanced nutrition are serious health problems in individuals with intellectual disabilities. The participants' chewing abilities, oral health and nutritional status were analysed in this study. Methods: Forty-five adult participants with intellectual disabilities were included.…

Background: People with Down syndrome often present with balance deficits, which compromise safety during daily activity. While evidence shows that exercise can improve balance in the Down syndrome population, it is unclear if a telehealth method will elicit similar benefits. We aimed to examine the effects of a virtual exercise program on balance…

Objectives: Characterise the circumstances associated with death during admission of adults with Down syndrome (DS) and to identify predictors of mortality. Patients and Methods: Observational study based on data on all emergent admissions of adults with DS to hospitals of the Spanish National Health System between 1997 and 2014. We analysed…

Literacy skills can assist in the navigation and enjoyment of adult life. For individuals who have reached adulthood without strong literacy skills, opportunities for continued literacy learning are few. Redesigning AAC technologies to support literacy skill development could extend literacy learning opportunities for adults with developmental…

This study was aimed at investigating the effectiveness of assisted therapy (ACT) on manual dexterity in older adults with Down syndrome (DS). Nine older participants with DS, aged 31-52 years old, completed a 30-min stationary cycling session, three times per week for eight weeks of ACT intervention, pedaling at 35% higher than voluntary speed.…

Background: A comprehensive multidisciplinary medical guideline for adults with Down syndrome is lacking in the Netherlands. In this study, we aim to explore parents' views on multidisciplinary care and identify which aspects of health care they find most important in the context of developing such a guideline. Method: This qualitative study used…

Purpose: Atypical vowel production contributes to reduced speech intelligibility in children and adults with Down syndrome (DS). This study compares the acoustic data of the corner vowels /i/, /u/, /ae/, and /[open back unrounded vowel]/ from speakers with DS against typically developing/developed (TD) speakers. Method: Measurements of the…

The high prevalence of sleep-related disorders is well documented in individuals with Down syndrome (DS). Given the association between physical activity (PA) and sleep in the typical populations, this study was the pilot study to examine this association through the parental report in this population. The total of forty-three individuals with DS…

Objectives: To describe the clinical and epidemiological characteristics of adult patients with Down syndrome admitted to Spanish hospitals between 1997 and 2014. Secondary goals were to study trend changes over time, and to analyse differences between patients admitted to medical and surgical departments. Patients and Methods: Retrospective…