The introduction of Computational Chemistry via "Molecular Modelling and Drug Design" course at undergraduate level has opened wide possibilities for students to expand their knowledge of quantum chemistry, organic reaction mechanisms, protein-ligand interactions, drug design, and probable "in vivo" behavior of drug candidates.…

The chlorination reaction of aromatic compounds is highly important for the synthesis of pharmaceutical products. As the most common chlorination reagent, chlorine is restricted from undergraduate laboratory experiment training due to its toxicity. In this work, we reported the chlorination of aromatic compounds with chlorine generated from the…

A two-year long-term workshop centered around a phenotypic whole-cell screening strategy for integrating cutting-edge knowledge and discovery-based laboratory experiences was developed to serve as a preparatory course for enhancing the teaching quality of the upper-level discovery-based research internship curriculum for pharmacy major…

Students often enter chemistry laboratory courses with a well-documented disconnect between their experiences outside the classroom and the procedures, concepts, and techniques that occur in our courses. Strong base, weak acid titration experiments are present in general chemistry laboratories but also relate to foods our students are familiar…

Introductory Chemistry laboratories must go beyond "cookbook" methods to illustrate how chemistry concepts apply to complex, real-world problems. In our case, we are preparing students to use their chemistry knowledge in the healthcare profession. The experiment described here explicitly models three important chemical concepts: dialysis…

The antibacterial chemical triclosan is a common component in personal care products but recently the subject of many reports concerning environmental toxicity and health impacts. Although triclosan concentration in a soap can be determined simply via high-performance liquid chromatography, this is a technique not routinely available in the…

In this laboratory experiment, lower- and upper-division students dissolved bismuth subsalicylate tablets in acid and precipitated the resultant Bi[superscript 3+] in solution with sodium phosphate for a gravimetric determination of bismuth subsalicylate in the tablets. With a labeled concentration of 262 mg/tablet, the combined data from three…

The use of in-class stories is an excellent way to keep a class interested in subject matter. Many organic chemistry classes are populated by nonchemistry majors, such as pre-med, pre-pharm, and biology students. Trivia questions are presented that are designed to show how organic chemistry is an important subject to students regardless of their…

An undergraduate research student was given the opportunity to take of ownership of her scientific knowledge by helping her to conduct research in the structural and nonstructural properties of drugs. The research highlighted that ketoprofen can be used to illustrate the structural and nonstructural properties of the research, helping the student…

Lists the 100 most frequently prescribed drugs, providing in tabular form the trade and generic name, and a brief introduction to the nature of each drug. (MLH)

Describes an elective course for many disciplines that requires a minimal knowledge of chemistry. (MLH)

Describes the case of a literature course which concentrates on readings concerned with certain aspects of drug use and a science course which analyzes the problems associated with such drug intake. (Author/GS)

Antianxiety agents are discussed in terms of their effects on the brain and central nervous system. Formulas for some substances, commonly prescribed as sedatives, are given. Includes a discussion on the toxicity and side effects of the drugs. (SA)