We examine the cost-effectiveness of treating epilepsy with anti-epileptic medicines in autistic children, looking at impacts on healthcare providers (in England, Ireland, Italy and Spain) and children's families (in Ireland). We find carbamazepine to be the most cost-effective drug to try first in children with newly diagnosed focal seizures. For…

Background: The STOMP agenda (Stopping Over-Medication of People with learning disabilities, autism, or both) drew focus to individuals with a diagnosis of a learning disability being prescribed psychotropic medication to manage 'behaviours that challenge'. The following study is an audit of two community learning disability services in the London…

Background: Lithium is well described in managing certain mental illnesses including in people with intellectual disabilities (ID). It requires regular monitoring particularly of serum levels and relevant biochemistry. However, existing monitoring protocols do not provide ID-specific guidance leading to increased risk of poor-quality care. This…

Puberty can be a particularly challenging time for adolescents who are transgender. Access to puberty blocking medication, commonly called 'puberty blockers', is considered an integral component of gender affirmative healthcare. Existing literature provides little insight into how parents of trans children entering into early adolescence navigate…

Collaboration between industry and universities is a driving force for scientific and technological advancements. Due to the role of AstraZeneca (AZ), a British-Swedish multinational pharmaceutical and biotechnology company, in combatting the COVID-19 pandemic, an analysis of the collaboration between the company and universities in the UK is of…

Background: Antipsychotic medications are used among 19%--58% of adults with intellectual disabilities to manage challenging behaviour against the NICE guideline recommendations. Studies show that it is possible to completely withdraw antipsychotics in about one third of adults with intellectual disabilities and a dose reduction of 50% or more in…

Background: The use of psychotropic medication to manage challenging behaviours of people with intellectual disabilities is a contentious issue which NHS England has now focused on. This paper looks to evaluate this within the multidisciplinary context. Method: Records of clients (n = 106) open to a Community Intellectual Disabilities team for…

Objective: Up to 50% of breast cancer survivors prescribed tamoxifen do not take it as prescribed for the full duration, which is linked to increased risk of recurrence and mortality. This paper tests the feasibility and acceptability of a self-directed psychoeducational intervention to support medication taking. Design: A single arm pre-post…

This paper presents the first empirical evidence on long-run trends in teacher mental health and wellbeing in England. We find that, although there has been a recent rise in mental health problems reported by teachers in England, this is mirrored by workers in other professions -- with little evidence of a simultaneous change in levels of personal…

Background: Intellectual disability (ID) is associated with polypharmacy particularly off-label psychotropics for "challenging behaviour." NHS England introduced the "stopping over medication of people with a learning disability (LD), autism or both" (STOMP) initiative. As ID services are a professionally diverse group, it is…

Introduction: e-Bug is an international educational resource for young people covering microbes, hygiene and antibiotics. e-Bug supports NICE guidance on changing public behaviour around antibiotic use. This study aimed to determine educators' views of the e-Bug teacher resources to inform further development and dissemination of e-Bug. Methods:…

Vaccines and treatments produced during the global coronavirus crisis demonstrated the importance of university research and teaching. There was widespread celebration of university-industry partnerships and collaborations across disciplines and geographical locations. However, simultaneously, higher education institutions in England faced serious…

Background: Previous research has found that people with learning disabilities are not given prescription information that is tailored to their needs. We wanted to find out people's information requirements. Materials and Methods: A questionnaire was co-produced by the authors and consultants with learning disabilities. It asked what information…

The term 'transition' is used to refer to the process of moving from child to adult services. Among child and adolescent mental health services attenders, young people with Attention Deficit Hyperactivity Disorder (ADHD) are less likely to transition successfully, but there is a gap in understanding their views and why they might disengage from…

The Scientific Method is the series of processes by which hypotheses, ideas and theories are shown to be true beyond a reasonable scientific doubt. Most science "fact" is expressed in terms of probabilities rather than certainties. Thus, by means of statistical calculations, researchers aim to determine whether an observed association…