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Direct linkHung, Kuo-Chuan; Chen, Jen-Yin; Hsing, Chung-Hsi; Hsu, Chih-Wei; Liu, Ping-Hsin; Chang, Ying-Jen; Chen, Jui-Yi; Chiu, Sheng-Fu; Sun, Cheuk-Kwan – Autism: The International Journal of Research and Practice, 2023
To investigate the association between labor epidural analgesia exposure and the risk of autism spectrum disorder in offspring, this meta-analysis reviewed relevant literature from Medline, Cochrane Library, Google Scholar, and EMBASE databases from inception to May 2022 to evaluate the overall adjusted risk of autism spectrum disorder in…
Descriptors: Autism Spectrum Disorders, Birth, Perinatal Influences, Risk
Roselyne Bulonza; Kim Watkins; Richard Parsons; Bruce Sunderland; Andrew Whitehouse; Rima Caccetta – Autism: The International Journal of Research and Practice, 2024
There is a significant variability in the prevalence of psychotropic medication use among young autistic persons worldwide and this is under-studied in Australia. Apart from risperidone, approved by the Therapeutic Goods Administration to manage challenging behaviour, the appropriateness of other psychotropic medications prescribed to young…
Descriptors: Foreign Countries, Autism Spectrum Disorders, Multiple Disabilities, Children
Tse, Andy C. Y.; Lee, Paul H.; Zhang, Jihui; Chan, Roy C. Y.; Ho, Amy W. Y.; Lai, Elvis W. H. – Autism: The International Journal of Research and Practice, 2022
Poor sleep quality and low behavioral functioning are commonly reported in children with autism spectrum disorder. This study examined the impact of exercise on sleep on melatonin level and behavioral functioning in the population. Children with autism spectrum disorder (n = 55; age = 10.97 ± 1.90) were randomly allocated to a morning jogging…
Descriptors: Children, Autism Spectrum Disorders, Exercise, Sleep
Lucy Beasant; Alba Realpe; Sarah Douglas; Lorcan Kenny; Dheeraj Rai; Nicola Mills – Autism: The International Journal of Research and Practice, 2024
The purpose of this study is to explore the views of autistic adults on randomised controlled trials, specifically on processes such as randomisation and blinding, to understand the barriers and facilitators for recruiting autistic people to randomised controlled trials involving medications. We conducted one-to-one interviews with 49 autistic…
Descriptors: Autism Spectrum Disorders, Adults, Attitudes, Randomized Controlled Trials
Shurtz, Logan; Schwartz, Chloe; DiStefano, Charlotte; McPartland, James C.; Levin, April R.; Dawson, Geraldine; Kleinhans, Natalia M.; Faja, Susan; Webb, Sara J.; Shic, Frederick; Naples, Adam J.; Seow, Helen; Bernier, Raphael A.; Chawarska, Katarzyna; Sugar, Catherine A.; Dziura, James; Senturk, Damla; Santhosh, Megha; Jeste, Shafali S. – Autism: The International Journal of Research and Practice, 2023
Children with autism spectrum disorder are prescribed various medications to address behavior and mood. In clinical trials, individuals taking concomitant psychotropic medications often are excluded to maintain homogeneity and prevent contamination of clinical endpoints. However, this choice may compromise the representativeness of the sample. In…
Descriptors: Autism Spectrum Disorders, Drug Therapy, Incidence, Child Behavior
Miot, Stéphanie; Chancel, Raphaël; Peries, Marianne; Crepiat, Sophie; Couderc, Sylvie; Pernon, Eric; Picot, Marie-Christine; Gonnier, Véronique; Jeandel, Claude; Blain, Hubert; Baghdadli, Amaria – Autism: The International Journal of Research and Practice, 2023
Multimorbidity, defined as having two or more chronic health conditions, is associated with elevated polypharmacy and mortality. Autism spectrum disorder is a whole-body chronic health condition in which comorbidities -- in particular co-occurring intellectual disability -- contribute to high clinical heterogeneity, polypharmacy and premature…
Descriptors: Comorbidity, Adults, Autism Spectrum Disorders, Intellectual Disability
Hegarty, John P., II; Zamzow, Rachel M.; Ferguson, Bradley J.; Christ, Shawn E.; Porges, Eric C.; Johnson, Jeffrey D.; Beversdorf, David Q. – Autism: The International Journal of Research and Practice, 2020
"Beta"-adrenergic antagonism (e.g. propranolol) has been associated with cognitive/behavioral benefits following stress-induced impairments and for some cognitive/behavioral domains in individuals with autism spectrum disorder. In this preliminary investigation, we examined whether the benefits of propranolol are associated with…
Descriptors: Adolescents, Adults, Autism, Pervasive Developmental Disorders
Bishop, Lauren; McLean, Kiley J.; Rubenstein, Eric – Autism: The International Journal of Research and Practice, 2021
Although epilepsy commonly presents with autism in children, it is currently unknown whether established estimates represent the prevalence and incidence of epilepsy in autistic adults. Our objective was to use population-level Medicaid data to determine prevalence, incidence, and antiepileptic drug use associated with epilepsy in a unique…
Descriptors: Epilepsy, Autism, Pervasive Developmental Disorders, Incidence
Simantov, Tslil; Pohl, Alexa; Tsompanidis, Alexandros; Weir, Elizabeth; Lombardo, Michael V; Ruigrok, Amber; Smith, Paula; Allison, Carrie; Baron-Cohen, Simon; Uzefovsky, Florina – Autism: The International Journal of Research and Practice, 2022
The sex bias in autism diagnosis suggests the involvement of sex-specific endocrine mechanisms during prenatal development, but these hormones affect health throughout life. Therefore, the current study examined the association of autism and autistic traits with conditions and symptoms related to the sex-steroid system in adult women. In total,…
Descriptors: Females, Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders)
Geurts, Hilde M.; McQuaid, Goldie A.; Begeer, Sander; Wallace, Gregory L. – Autism: The International Journal of Research and Practice, 2022
Prior research suggests that autistic adults are at increased risk for developing the core motor components of Parkinson's disease (i.e. parkinsonism) although knowledge is limited to date. Therefore, we explore: (1) the prevalence of both continuous self-reported motor features typical of parkinsonism and the screen positivity rate for…
Descriptors: Older Adults, Autism, Pervasive Developmental Disorders, At Risk Persons
Schwartzman, Jessica M.; Williams, Zachary J.; Corbett, Blythe A. – Autism: The International Journal of Research and Practice, 2022
Prevalence rates of depression are higher in autistic youth than neurotypical peers, yet the effects of autism spectrum disorder diagnosis and sex on depressive symptom severity remain incompletely understood, particularly in specific age groups. Using the Children's Depression Inventory, Second Edition, this study explored diagnostic- and…
Descriptors: Depression (Psychology), Autism, Pervasive Developmental Disorders, Gender Differences
Hardan, Antonio Y.; Hendren, Robert L.; Aman, Michael G.; Robb, Adelaide; Melmed, Raun D.; Andersen, Kristen A.; Luchini, Rachel; Rahman, Rezwanur; Ali, Sanjida; Jia, X Daniel; Mallick, Madhuja; Lateiner, Jordan E.; Palmer, Robert H.; Graham, Stephen M. – Autism: The International Journal of Research and Practice, 2019
Three phase 2 trials were conducted to assess the efficacy and long-term safety of weight-based memantine extended release (ER) treatment in children with autism spectrum disorder. MEM-MD-91, a 50-week open-label trial, identified memantine extended-release treatment responders for enrollment into MEM-MD-68, a 12-week randomized, double-blind,…
Descriptors: Children, Autism, Pervasive Developmental Disorders, Drug Therapy
Tint, Ami; Brown, Hilary K.; Chen, Simon; Lai, Meng-Chuan; Tarasoff, Lesley A.; Vigod, Simone N.; Parish, Susan; Havercamp, Susan M.; Lunsky, Yona – Autism: The International Journal of Research and Practice, 2021
While an increasing number of girls and women are being identified with autism, we know little about the health of reproductive-aged autistic women. Our objectives were to (1) describe health characteristics of reproductive-aged autistic women who could potentially become pregnant and (2) compare these characteristics with those of non-autistic…
Descriptors: Autism, Pervasive Developmental Disorders, Females, Foreign Countries
Jonkman, Kim M.; Back, Elisa; Begeer, Sander – Autism: The International Journal of Research and Practice, 2023
Autism is a heterogeneous diagnosis with symptoms that present in different ways. There is a large variety of interventions for autistic individuals. However, little is known about who chooses which specific interventions. We aimed to explore intervention prevalence and predict intervention use, based on demographic and autism-specific…
Descriptors: Autism Spectrum Disorders, Intervention, Children, Adolescents
Saloner, Brendan; Barry, Colleen L. – Autism: The International Journal of Research and Practice, 2019
Almost all states have insurance coverage mandates for childhood autism spectrum disorder treatment, yet little is known about how mandates affect spending and service use. We evaluated a 2011 Kansas law mandating comprehensive coverage of autism spectrum disorder treatments in the State Employee Health Plan. Data were extracted from the Kansas…
Descriptors: Autism, Pervasive Developmental Disorders, Health Insurance, State Legislation
