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Showing 1 to 15 of 67 results Save | Export
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Antonia Fruntke; Juliana Hu¨lsmann; Lennart Hendrik Skodda; Benedikt Blu¨mbott; Maren Godmann; Andreas Koschella; Thorsten Heinzel; Thomas Heinze; Timm Wilke – Journal of Chemical Education, 2025
The subject of pharmaceutical research has traditionally focused on drugs with systemic effects. However, contemporary approaches aspire to achieve targeted drug delivery, with the aim of combatting infections with a precise immune response. Active substances are encapsulated in nanoparticles, transported through the body, and selectively released…
Descriptors: Drug Therapy, Science Laboratories, Pharmacology, Chemistry
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Custo´dia do S. Cruz Fonseca – Journal of Chemical Education, 2025
Since ancient times, man has prepared medicines and used them in healing practices. Therefore, there has always been a great interest in the part of people in general and students in particular about medicines. The "Medicines, the Haute Couture of Pharmacy" summer camp has the objective to promote and improve the literacy in medicines…
Descriptors: Pharmacy, Summer Programs, Camps, High School Students
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Stephanie L. Mitchell; Jill S. McCourt; Diane J. Nesset-Tollefson; Gabrielle L. Kimball; Jasmine N. Mikesell; Emily J. Tollefson; Erin E. Carlson – Journal of Chemical Education, 2023
Common over-the-counter medicines can be an exciting entry point for introducing students to the interesting chemistries that they encounter in their daily lives. In this inquiry-based activity, students are tasked with using a list of given supplies and information about four medications (Aspirin, Tums, Pepto-Bismol, and Tylenol) to design three…
Descriptors: Medicine, Chemistry, Science Education, Active Learning
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Faville, Scott C.; Harris-Hamdscomb, Kes; Harker, Owain; Mattison, Stephanie; Tamorite, Hajie; Bristowe, Joshua; Daly, Daniel; Ege, Raissa; He, Haoyuan; Jones, Julian; McCorkindale, Abby; Mei, Kerry; Monson, Ashleigh; Moree, Lana; Perkovic, Finley; Rickerby, Georgia; Robinson, Jack; Rudkin, Felix; Whibley, Luke; Worthington, Rebecca; Ennis, Courtney; de la Harpe, Sara; Brind, Thomasin; Hopkins, Andrew; Winefield, Kaleb; Hendrickx, Sarah; Caljon, Guy; Perry, Benjamin; Vernall, Andrea J. – Journal of Chemical Education, 2022
An undergraduate laboratory was developed as part of the Drugs for Neglected Diseases "initiative's" Open Synthesis Network. This activity aimed to develop new compounds efficacious against visceral leishmaniasis. Students successfully synthesized, purified, and characterized ten different benzoxazole amides that were sent for biological…
Descriptors: College Science, Undergraduate Students, Laboratory Experiments, Diseases
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Chengxuan Guo; Nicole Wendel; Ally Lee; Shonda Monette; Brian Morrison; Dominic Frisbie; Earlene Erbe; Rene´e S. Cole; Max Lei Geng – Journal of Chemical Education, 2024
The pharmaceutical and medicine manufacturing industry has become the largest industrial sector for the employment of chemists, indicating a need for experiments with a pharmaceutical sciences context in the undergraduate chemistry curriculum. In the pharmaceutical industry, testing drug dissolution is a key analytical task for solid oral dosage…
Descriptors: Undergraduate Students, Chemistry, Science Instruction, Laboratory Experiments
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Candela, Maria Fernanda; Arenas, Nelson E.; Caicedo, Obradith; Malagon, Andres – Journal of Chemical Education, 2021
The inhibition of porcine pancreatic lipase by the drug orlistat was studied through a series of activities that combine experimental and computational procedures. The enzymatic activity of the lipase was determined by measuring enzyme kinetics and calculating parameters such as K[subscript m] and V[subscript max] from experimental data. Assays of…
Descriptors: Biochemistry, Drug Therapy, Kinetics, Measurement
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Audrey G. Fikes; Melissa C. Srougi – Journal of Chemical Education, 2023
The application of chemistry concepts in biological settings plays an important role in the interdisciplinary field of drug discovery and development. This is true for molecular docking, where an understanding of intermolecular forces and noncovalent interactions is useful for rational drug design and development. Here we report the design and use…
Descriptors: Chemistry, Science Instruction, Molecular Structure, Drug Therapy
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Xiangli He; Ying Huang; Zhongyu Xu; Xi Liu; Zhaomin Xu; Lei Ma; Yuzheng Zhao; Jin Huang – Journal of Chemical Education, 2023
Enzymes provide attractive targets for drug development. Quantitative analysis of enzyme reactions can lead to rational drug discovery. For undergraduates majoring in biochemistry or pharmacy and engaged in drug discovery-related work, it is essential to acquire a comprehensive understanding of enzyme kinetics, including experimental methods and…
Descriptors: Undergraduate Students, College Science, Biochemistry, Pharmaceutical Education
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Aisha Alsfouk – Journal of Chemical Education, 2023
Fourth- and fifth-year pharmacy students attending integrated pharmacotherapy courses at Princess Nourah bint Abdulrahman University completed a medicinal chemistry assignment using computer-based technology. This written assignment encompassed multiple components requiring the use of free online resources to study and illustrate several stages of…
Descriptors: Undergraduate Students, Pharmaceutical Education, Medicine, Chemistry
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Elizabeth W. Kelley – Journal of Chemical Education, 2023
The pharmaceutical industry has been a major player in improving life expectancies and driving chemistry employment. While computational chemistry tools increasingly guide pharmaceutical research decisions, high school and undergraduate chemistry curricula do not reflect the prevalence of such techniques. Incorporation of computational tools into…
Descriptors: Secondary School Science, High School Students, Chemistry, Computer Assisted Design
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Coyle, Robert; Farrell, Garrett; McFadden, Kim; Warren, Patricia – Journal of Chemical Education, 2021
This practical is aimed at students who have been introduced to the tableting process, drug delivery systems, and dissolution. The student can design and manufacture a tablet investigating the effect of excipients and their role in tablet design and then generate a release profile of the tablet by using a dissolution apparatus, flow-through cell,…
Descriptors: Chemistry, Science Instruction, Teaching Methods, Drug Therapy
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Wanmei Li; Yani Ouyang; Jun Xu; Pengfei Zhang – Journal of Chemical Education, 2022
Medicinal chemistry, as the core curriculum of the pharmaceutical engineering major, contains complex knowledge systems and scattered knowledge points. A medicinal chemistry course covers more than 50kinds of drugs divided into 11 categories including antibiotics, antiparasitic drugs, anesthetics, nonsteroidal anti-inflammatory drugs, and nervous…
Descriptors: Student Centered Learning, Cooperative Learning, Teamwork, Science Instruction
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Oliver B. Andrew; James Sherwood; Glenn A. Hurst – Journal of Chemical Education, 2022
A laboratory experiment was developed to introduce systems thinking and green chemistry concepts through the synthesis of the antidepressant and smoking cessation aid, bupropion hydrochloride. The traditional synthesis has several issues from a green chemistry perspective: it uses the toxic solvents N-methylpyrrolidinone (NMP) and dichloromethane…
Descriptors: Drug Therapy, Depression (Psychology), Biochemistry, Laboratory Experiments
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Siow-Ping Tan; Xin-Yi Keng; Bryan Chi-Wah Lim; Sook Yee Liew; Mohd Azlan Nafiah – Journal of Chemical Education, 2023
Plant-derived natural products are an important source of potential medicines and continue to have a major impact on the drug discovery process. Natural product discovery assignments provide an opportunity to present various experimental techniques to undergraduate students in introductory medicinal chemistry. This assignment was developed to…
Descriptors: Undergraduate Students, College Science, Chemistry, Recycling
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Kearney, Mary-Carmel; Larran~eta, Eneko – Journal of Chemical Education, 2021
The aim of this work was to design, deliver, and evaluate group case studies focused on the integration of analytical and medicinal chemistry with pharmacy practice. A patient-centered beta-blocker workshop was developed and delivered to year two MPharm and BSc students. Students were tasked with reviewing patient clinical data along with…
Descriptors: Case Method (Teaching Technique), Pharmaceutical Education, Workshops, Drug Therapy
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