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Ben Younan; Mikaela Jorgensen; Glenys Holt; Monica Cuskelly; Manya Angley; Robyn Wallace; Juanita Breen; Donna Gillies – Journal of Applied Research in Intellectual Disabilities, 2025
Background: People with neurodevelopmental disabilities are frequently prescribed or administered psychotropic medication, particularly to manage behaviours of concern. Reducing inappropriate psychotropic use has been the target of international research and policy for several decades. Methods: Six electronic databases were searched for…
Descriptors: Meta Analysis, Drug Therapy, Intervention, Developmental Disabilities
Ulrich Elbing; Sebastian Appelbaum; Thomas Ostermann – Journal of Intellectual Disabilities, 2024
This study aims to contribute to the knowledge about lacking or contradictory effects of benzodiazepine on hyperaroused or aggressive behaviour in persons with intellectual disability (ID). We conducted a retrospective and natural case study in a person with mild ID and multiple adverse childhood experiences (ACE), using routine diary data…
Descriptors: Mild Intellectual Disability, Drug Therapy, Behavior Problems, Symptoms (Individual Disorders)
Busch, Louis; Saini, Valdeep; Budin, Radek; Jones, Roland M. – Journal of Applied Research in Intellectual Disabilities, 2023
Adults living with intellectual and developmental disabilities are often prescribed psychotropic medication on an "as needed" basis (PRN) in response to behavioural challenges. In the present study we conducted a retrospective analysis of medication administration records in the 6-months preceding and following discharge of 11 adults…
Descriptors: Adults, Patients, Intellectual Disability, Developmental Disabilities
Trine Lise Bakken; Jane Margrete Askeland Hellerud; Arvid Nikolai Kildahl; Ann Magritt Solheim-Inderberg; Oddbjørn Hove; Sissel Berge Helverschou – Journal of Autism and Developmental Disorders, 2025
Autistic people with intellectual disabilities appear to be at increased risk of schizophrenia. While current recommendations emphasize adapting interventions used for people with schizophrenia in general, few studies to date have investigated treatment of co-occurring schizophrenia in this specific population. To explore what interventions are…
Descriptors: Autism Spectrum Disorders, Intellectual Disability, Schizophrenia, Comorbidity
Laermans, P.; Morisse, F.; Lombardi, M.; Gérard, S.; Vandevelde, S.; de Kuijper, G.; Audenaert, K.; Claes, C. – International Journal of Developmental Disabilities, 2023
Introduction: Adults with intellectual disabilities have an increased vulnerability to mental health problems and challenging behaviour. In addition to psychotherapeutic or psychoeducational methods, off-label pharmacotherapy, is a commonly used treatment modality. Objective: The aim of this study was to establish evidence-based guideline…
Descriptors: Adults, Intellectual Disability, Drug Therapy, Behavior Problems
Ryan Holmes; Lucy Kearney; Sheetal Gopal; Inderpal Daddi – British Journal of Learning Disabilities, 2024
Background: The STOMP agenda (Stopping Over-Medication of People with learning disabilities, autism, or both) drew focus to individuals with a diagnosis of a learning disability being prescribed psychotropic medication to manage 'behaviours that challenge'. The following study is an audit of two community learning disability services in the London…
Descriptors: Drug Therapy, Behavior Modification, Behavior Problems, Learning Disabilities
Lloyd, Blair P.; Weaver, Emily S.; Torelli, Jessica N.; Pollack, Marney S.; Fareed, Sunya A.; Maxwell-Horn, Angela C. – American Journal on Intellectual and Developmental Disabilities, 2021
The purpose of the current study was to explore the scientific utility of two behavior analytic assessments (i.e., progressive ratio and demand assessments) for psychotropic medication evaluation. For a sample of 23 children with disabilities who were prescribed medication, we conducted a series of generalizability and optimization studies to…
Descriptors: Disabilities, Children, Drug Therapy, Behavior Problems
García-Domínguez, Laura; Navas, Patricia; Verdugo, Miguel Ángel; Arias, Víctor B.; Gómez, Laura E. – Journal of Applied Research in Intellectual Disabilities, 2022
Background: Psychotropic medication is frequently administered to people with intellectual disability with mental health and/or behavioural problems, instead of other non-pharmacological interventions. This study describes the mental health and behavioural problems of people aging with intellectual disability, their psychotropic medication intake,…
Descriptors: Drug Therapy, Mental Disorders, Behavior Problems, Intellectual Disability
Shurtz, Logan; Schwartz, Chloe; DiStefano, Charlotte; McPartland, James C.; Levin, April R.; Dawson, Geraldine; Kleinhans, Natalia M.; Faja, Susan; Webb, Sara J.; Shic, Frederick; Naples, Adam J.; Seow, Helen; Bernier, Raphael A.; Chawarska, Katarzyna; Sugar, Catherine A.; Dziura, James; Senturk, Damla; Santhosh, Megha; Jeste, Shafali S. – Autism: The International Journal of Research and Practice, 2023
Children with autism spectrum disorder are prescribed various medications to address behavior and mood. In clinical trials, individuals taking concomitant psychotropic medications often are excluded to maintain homogeneity and prevent contamination of clinical endpoints. However, this choice may compromise the representativeness of the sample. In…
Descriptors: Autism Spectrum Disorders, Drug Therapy, Incidence, Child Behavior
Latent Class Analysis Identifies Distinctive Behavioral Subtypes in Children with Fragile X Syndrome
Walter E. Kaufmann; Melissa Raspa; Carla M. Bann; Julia M. Gable; Holly K. Harris; Dejan B. Budimirovic; Reymundo Lozano – Journal of Autism and Developmental Disorders, 2024
Fragile X syndrome (FXS) is characterized by variable neurobehavioral abnormalities, which leads to difficulties in developing and evaluating treatments and in determining accurate prognosis. We employed a pediatric cross-sectional sample (1,072 males, 338 females) from FORWARD, a clinic-based natural history study, to identify behavioral subtypes…
Descriptors: Symptoms (Individual Disorders), Children, Genetic Disorders, Intellectual Disability
Orla O'Regan; Yvonne Doyle; Marguerite Murray; Vera J. C. McCarthy; Mohamad M. Saab – International Journal of Developmental Disabilities, 2024
Background: Challenging behaviours are common among children and adolescents with intellectual disabilities. Such behaviours often result in poor quality of life outcomes such as physical injury, difficulties with relationships and community integration. Aim: This systematic review aimed to synthesise evidence from studies that assessed the effect…
Descriptors: Behavior Problems, Behavior Modification, Children, Adolescents
Vasa, Roma A.; Singh, Vini; McDonald, Rachel G.; Mazefsky, Carla; Hong, Ji Su; Keefer, Amy – Journal of Autism and Developmental Disorders, 2022
Research indicates that children with autism spectrum disorder (ASD) frequently exhibit dysregulation, which refers to poorly coordinated affective, behavioral, and cognitive responses to a given situation. We examined the characteristics of dysregulation in children presenting to a multidisciplinary ASD clinic for an ASD diagnostic evaluation.…
Descriptors: Children, Autism, Pervasive Developmental Disorders, Behavior Problems
Nicole Edwards; Catherine Franklin; Julie King; Hanna Watling – Journal of Mental Health Research in Intellectual Disabilities, 2024
Background: Psychiatrists prescribe the psychotropic medication that is used to manage behaviors of concern (BOC) in people with intellectual disability (ID) (i.e., chemical restraint), and their attitudes and perceptions towards this treatment are important topics for study. Methods: 133 Queensland psychiatrists and psychiatry trainees completed…
Descriptors: Foreign Countries, Psychiatry, Professional Personnel, Trainees
Armstrong, Emily F.; Maricle, Denise E. – Communique, 2023
Due to the increased risks of neurocognitive impairment when a child is diagnosed with Type 1 diabetes (T1D) at an early age, early identification and assessment are critical. A study by Nadebaum et al. (2012) found that cognition is impaired in a significant number of children at the time of diagnosis, and those who are initially impaired show a…
Descriptors: Diabetes, School Psychologists, Symptoms (Individual Disorders), Neurological Impairments
de Kuijper, Gerda M.; Den Besten-van Ravenswaaij, Janneke J. C.; Hoekstra, Pieter J.; de Bildt, Annelies – Journal of Applied Research in Intellectual Disabilities, 2023
Background: Interventions for challenging behaviours in individuals with intellectual disabilities benefit from outcome monitoring that takes clients' preferences into account. We determined clients' and representatives' preferred outcome domains and measures to secure their involvement in treatment decisions for challenging behaviours. Method: We…
Descriptors: Behavior Problems, Intellectual Disability, Outcomes of Treatment, Intervention