The realist review/synthesis has become an increasingly prominent methodological approach to evidence synthesis that can inform policy and practice. While there are publication standards and guidelines for the conduct of realist reviews, published reviews often provide minimal detail regarding how they have conducted some methodological steps.…

Systematic reviews and meta-analyses are essential for drawing conclusions regarding etiologic associations between exposures or interventions and health outcomes. Observational studies comprise a substantive source of the evidence base. One major threat to their validity is residual confounding, which may occur when component studies adjust for…

Policy and program decisions typically involve selecting one choice from among a set of options, and research about the effect of those options can help inform the decision process. However, for the research to be useful, decision makers need a way of drawing accurate lessons from what often can be a large assortment of relevant studies.…