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Direct linkPinkston, Jonathan W.; Lamb, R. J. – Journal of the Experimental Analysis of Behavior, 2012
When given to pigeons, the direct-acting dopamine agonist apomorphine elicits pecking. The response has been likened to foraging pecking because it bears remarkable similarity to foraging behavior, and it is enhanced by food deprivation. On the other hand, other data suggest the response is not related to foraging behavior and may even interfere…
Descriptors: Animals, Brain, Biochemistry, Experiments
Albrecht, Doris – Learning & Memory, 2007
It is known from studies outside the brain that upon binding to its receptor, angiotensin-(1-7) elicits the release of prostanoids and nitric oxide (NO). Cyclooxygenase (COX) is a key enzyme that converts arachidonic acid to prostaglandins. Since there are no data available so far on the role of COX-2 in the amygdala, in a first step we…
Descriptors: Stimulation, Brain, Animals, Memory
Holahan, Matthew R.; Honegger, Kyle S.; Tabatadze, Nino; Routtenberg, Aryeh – Learning & Memory, 2007
Previous reports have shown that overexpression of the growth- and plasticity-associated protein GAP-43 improves memory. However, the relation between the levels of this protein to memory enhancement remains unknown. Here, we studied this issue in transgenic mice (G-Phos) overexpressing native, chick GAP-43. These G-Phos mice could be divided at…
Descriptors: Animals, Alzheimers Disease, Memory, Animal Behavior
Steward, Oswald; Huang, Fen; Guzowski, John F. – Learning & Memory, 2007
Stimulation paradigms that induce perforant path long-term potentiation (LTP) initiate phosphorylation of ERK1/2 and induce expression of a variety of immediate early genes (IEGs). These events are thought to be critical components of the mechanism for establishing the changes in synaptic efficacy that endure for hours or longer. Here we show that…
Descriptors: Stimulation, Seizures, Animals, Behavior Modification
O'Carroll, Colin M.; Martin, Stephen J.; Sandin, Johan; Frenguelli, Bruno; Morris, Richard G. M. – Learning & Memory, 2006
The persistence of new memory traces in the hippocampus, encoded following appropriate activation of glutamatergic receptors and the induction of synaptic plasticity, can be influenced by heterosynaptic activation of neuromodulatory brain systems. We therefore investigated the effects of a hippocampus-specific blockade of dopamine D1/D5 receptors…
Descriptors: Intervals, Brain, Animals, Animal Behavior
Holscher, Christian; Schmid, Susanne; Pilz, Peter K. D.; Sansig, Gilles; van der Putten, Herman; Plappert, Claudia F. – Learning & Memory, 2005
Metabotropic glutamate receptors (mGluRs) are known to play a role in synaptic plasticity and learning. We have previously shown that mGluR7 deletion in mice produces a selective working memory (WM) impairment, while other types of memory such as reference memory remain unaffected. Since WM has been associated with Theta activity (6-12 Hz) in…
Descriptors: Animals, Short Term Memory, Neurology, Neurological Organization
