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Direct linkJianjun Ou; Robert C. Smith; Russell H. Tobe; Jingjing Lin; Jen Arriaza; Jed W. Fahey; Ruiting Liu; Ying Zeng; Yanan Liu; Lian Huang; Yidong Shen; Yamin Li; Daomeng Cheng; Brian Cornblatt; John M. Davis; Jingping Zhao; Renrong Wu; Hua Jin – Journal of Autism and Developmental Disorders, 2024
Sulforaphane has been reported to possibly improve core symptoms associated with autism spectrum disorders from mostly small size studies. Here we present results of a larger randomized clinical trial (N = 108) in China. There were no significant changes in caregiver rated scales between sulforaphane and placebo groups. However, clinician rated…
Descriptors: Drug Therapy, Outcomes of Treatment, Autism Spectrum Disorders, Randomized Controlled Trials
Lucy Beasant; Alba Realpe; Sarah Douglas; Lorcan Kenny; Dheeraj Rai; Nicola Mills – Autism: The International Journal of Research and Practice, 2024
The purpose of this study is to explore the views of autistic adults on randomised controlled trials, specifically on processes such as randomisation and blinding, to understand the barriers and facilitators for recruiting autistic people to randomised controlled trials involving medications. We conducted one-to-one interviews with 49 autistic…
Descriptors: Autism Spectrum Disorders, Adults, Attitudes, Randomized Controlled Trials
Salomone, Erica; Settanni, Michele; McConachie, Helen; Suma, Katharine; Ferrara, Federica; Foletti, Giulia; Salandin, Arianna; Brown, Felicity L.; Brown, Felicity L.; Pacione, Laura; Shire, Stephanie; Servili, Chiara; Adamson, Lauren B. – Journal of Autism and Developmental Disorders, 2022
Parents of children with ASD (N = 86; mean age 44.8 months; 67 boys) were randomized to either WHO Caregiver Skills Training (CST) delivered in public health settings in Italy or enhanced treatment-as-usual. Primary blinded outcomes were 3-months post-intervention change scores of autism severity and engagement during caregiver-child interaction.…
Descriptors: Caregiver Training, Skill Development, Public Health, Health Services
