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Interaction of Dopamine Transporter Gene and Observed Parenting Behaviors on Attention-Deficit/Hyperactivity Disorder: A Structural Equation Modeling Approach
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Li, James J.; Lee, Steve S. – Journal of Clinical Child and Adolescent Psychology, 2013
Emerging evidence suggests that some individuals may be simultaneously more responsive to the effects from environmental adversity "and" enrichment (i.e., differential susceptibility). Given that parenting behavior and a variable number tandem repeat polymorphism in the 3'untranslated region of the dopamine transporter (DAT1) gene are…
Descriptors: Structural Equation Models, Genetics, Attention Deficit Hyperactivity Disorder, Parenting Styles
Children with ADHD Symptoms Show Decreased Activity in Ventral Striatum during the Anticipation of Reward, Irrespective of ADHD Diagnosis
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van Hulst, Branko M.; de Zeeuw, Patrick; Bos, Dienke J.; Rijks, Yvonne; Neggers, Sebastiaan F. W.; Durston, Sarah – Journal of Child Psychology and Psychiatry, 2017
Background: Changes in reward processing are thought to be involved in the etiology of attention-deficit/hyperactivity disorder (ADHD), as well as other developmental disorders. In addition, different forms of therapy for ADHD rely on reinforcement principles. As such, improved understanding of reward processing in ADHD could eventually lead to…
Descriptors: Attention Deficit Hyperactivity Disorder, Task Analysis, Reinforcement, Therapy
Is Sensory Over-Responsivity Distinguishable from Childhood Behavior Problems? A Phenotypic and Genetic Analysis
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Van Hulle, Carol A.; Schmidt, Nicole L.; Goldsmith, H. Hill – Journal of Child Psychology and Psychiatry, 2012
Background: Although impaired sensory processing accompanies various clinical conditions, the question of its status as an independent disorder remains open. Our goal was to delineate the comorbidity (or lack thereof) between childhood psychopathology and sensory over-responsivity (SOR) in middle childhood using phenotypic and behavior-genetic…
Descriptors: Attention Deficit Hyperactivity Disorder, Anxiety Disorders, Behavior Problems, Siblings
Components of Childhood Impulsivity and Inattention: Child, Family, and Genetic Correlates
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Ruf, Helena T.; Schmidt, Nicole L.; Lemery-Chalfant, Kathryn; Goldsmith, H. Hill – European Journal of Developmental Science, 2008
Impulsivity and inattention are key constructs at the interface of temperament and domains of childhood behavioral problems, such as ADHD and ODD. A multi-method, multi-source assessment of impulsivity and inattention was conducted with 256 families of twins at a mean age of 8-9 years from an epidemiologically defined community sample. Analysis of…
Descriptors: Attention Deficit Hyperactivity Disorder, Behavior Problems, Child Behavior, Genetics
Sleep and COMT Polymorphism in ADHD Children: Preliminary Actigraphic Data
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Gruber, Reut; Grizenko, Natalie; Schwartz, George; Amor, Leila Ben; Gauthier, Julie; de Guzman, Rosherrie; Joober, Ridha – Journal of the American Academy of Child & Adolescent Psychiatry, 2006
Objective: To examine whether COMT (catechol-O-methyltransferase) polymorphism modulates aspects of sleep in children diagnosed with attention-deficit/hyperactivity disorder (ADHD). Method: Nightly sleep actigraphic recordings during a double-blind, placebo-controlled, crossover clinical study (1 week of 0.5 mg/kg MPH; 1 week of placebo) were…
Descriptors: Attention Deficit Hyperactivity Disorder, Sleep, Children, Drug Therapy
Common and Specific Genetic Influences on Aggressive and Nonaggressive Conduct Disorder Domains
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Gelhorn, Heather; Stallings, Michael; Young, Susan; Corley, Robin; Rhee, Soo Hyun; Hopfer, Christian; Hewitt, John – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To explore the genetic and environmental influences on DSM-IV conduct disorder (CD) aggressive and nonaggressive subscales, taking into account age and sex differences. Method: A community sample of 1,100 twin pairs (ages 11-18) was interviewed using the Diagnostic Interview Schedule for Children. Bivariate analyses, using variable…
Descriptors: Environmental Influences, Antisocial Behavior, Genetics, Twins