Explains the structural organization of DNA by providing information on the primary, secondary, tertiary, and higher organization levels of the molecule. Also includes illustrations and descriptions of sign-inversion and rotating models for supercoiling of DNA. (ML)

Genetic diseases in children present difficulties to the children themselves and to their families. This article reviews the features of genetic disease, stresses surrounding diagnosis, difficulties associated with each developmental stage, other sources of psychosocial stress on the family (e.g., finances, hospitalization, placement decisions),…

Compares two methods (batch and continuous) in which microorganisms are used to produce industrial chemicals. Describes batch and continuous stirred-tank reactors and offers reasons why the batch method may be preferred. (JN)

Outlines advances in the microbial production of pharmaceuticals, including the manufacture of penicillin and other antibiotics, vitamins, hormones, alkaloids, antitumor drugs, and interferons. (CS)

Compares traditional and newer methods by which microorganisms are used to produce industrial chemicals. Includes a discussion of economic considerations and new genetic methods in programing microorganisms. Details methods for producing enzymes, aliphatic organic compounds, amino acids, ethanol, n-butanol, and alkene oxides. (CS)

Presents an overview of the field of industrial microbiology, providing historical backgrounds of scientific discoveries in the field and descriptions of industrially important microorganisms. Applied research in industry is also detailed, with mention of gene amplification, DNA recombination, pharmaceutical approaches, and detoxification and…

Traces the development of the field of industrial microbial genetics, describing a range of techniques for genetic programing. Includes a discussion of site-directed mutagenesis, protoplast fusion, and recombinant DNA manipulations. (CS)

Elucidates strategies for applying microbiological techniques to traditional agricultural practices. Discusses the manipulation of microorganisms that live with plants and also the problems involved in the introduction of new genes into crop plants by recombinant DNA methods. (CS)

Describes industrially important yeasts, molds, bacteria, and actinomycetes. Discussed in detail are microbial products, such as primary metabolites, secondary metabolites, enzymes, and capsular polysaccharides. Traces the historical background of human cell culture, mentioning recombinant DNA research and hybridization of normal mammalian cells…

This book includes more than 500 entries describing advances in the treatment of disease and the understanding of human health. The emphasis is on significant advances in diseases, treatments, and health issues. Topics included are: alternative or nonwestern medicine; anesthesia and analgesia; antibiotics; cancer; cell biology and physiology;…