Abstract Microbiome study requires both molecular techniques and bioinformatics skills, which are challenging for biologists to participate in this growing field. To introduce microbiome concepts and skills to students, a 6-week wet-lab and bioinformatics course for undergraduates was implemented through the project-based learning (PBL) approach.…

Virtual Labs (vLabs) have been gaining popularity in high school and undergraduate education, but there are few studies looking at their use in graduate-level courses. In this study, we investigated the use of six Labster vLabs assigned as homework in a graduate-level in-person Genomic Methodologies course at the University of Toronto. This course…

Animal models are widely used in laboratory practicals in biomedical disciplines. However, experiments involving animal work are usually time-and-labor consuming. It is also costly to run an animal lab and the animal caring/holding request special training. Here we present a laboratory course design that provides students with wet lab experience…

Innovative approaches to teaching genetics are essential for improving student engagement and comprehension in this challenging field. Laboratory-based instruction enhances engagement with the subject while fostering the development of practical competencies and deepening comprehension of theoretical concepts. However, constraints on time and…

Collaborative problem-solving (CPS) is increasingly essential in both scientific practice and modern education, yet remains difficult to embed authentically in classrooms. This study addressed that gap by integrating CPS into a ninth-grade biology lesson using a smartphone-based asymmetric simulation. The innovative three-phase instructional…

Background: Spatial ability has an important place in science education, which is effective in raising future scientists. Although not in large numbers, studies show that teachers' spatial abilities somehow affect their teaching practices in the classroom and thus the spatial abilities of their students. Purpose: This study aimed to investigate…

This paper analyzes Sim-Evolution, an educational simulator designed to help teachers presenting three basic principles of the theory of evolution by natural selection (TENS): the trait variation within a population, the heritability of trait variation, and the selective survival based on heritable traits. Sim-Evolution focuses on high school…

Biology and biochemistry students must learn to visualize and comprehend the complex three-dimensional (3D) structures of macromolecules such as proteins or DNA. However, most tools available for teaching biomolecular structures typically operate in two dimensions. Here, we present protocols and pedagogical approaches for using immersive augmented…

COVID-19 has changed about every aspect of life including how we teach in higher education. Laboratory experiments vital for learning hands-on techniques are limited due to social distancing requirements and increased numbers of distance-learning students. The solution to loss of hands-on activities has been to compensate with virtual laboratory…

The essence of Genetics lies in the understanding of the concepts of Central Dogma of Molecular Biology. Although these ideas are fundamental to the field, they are notoriously difficult to understand and visualize. While simulation-based instructional materials are found to improve the teaching-learning process in science education, little has…

Despite the advantages proffered by technology in science education, little has been done to develop and validate innovative technology-based instructional materials on Central Dogma of Molecular Biology. It is imperative to test any newly generated instructional materials to validate their quality before being widely used. Hence, this study aimed…

The commercialization of virtual reality (VR) hardware has enabled the use of VR as an educational tool. We describe how a VR platform was used to create molecular visualizations using standard PDB files with the purpose of delivering biochemistry and cellular biology lessons for undergraduates. Specifically, we describe two new software modules,…

The creation and analysis of models is integral to all scientific disciplines, and modeling is considered a core competency in undergraduate biology education. There remains a gap in understanding how modeling activities may support changes in students' neural representations. The aim of this study was to evaluate the effects of simulating a model…

Model-based instruction offers numerous benefits to students, including increased content knowledge and critical thinking. This study explored the differences in the knowledge outcomes and reasoning processes employed by undergraduate students in an introductory biology lab as they constructed, revised, and simulated a computational model of a…

In order to investigate the complexity of mutations, a computational approach named Genome Evolution by Matrix Algorithms ("GEMA") has been implemented. GEMA models genomic changes, taking into account hundreds of mutations within each individual in a population. By modeling of entire human chromosomes, GEMA precisely mimics real…