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Showing 1 to 15 of 54 results Save | Export
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Andrew J. Tonsager; Laurie A. Stargell – Biochemistry and Molecular Biology Education, 2025
CRISPR-Cas9 technology is an established, powerful tool for genome editing through the ability to target specific DNA sequences of interest for introduction of desired genetic modifications. CRISPR-Cas9 is utilized for a variety of purposes, ranging from a research molecular biology tool to treatment for human diseases. Due to its prominence…
Descriptors: Undergraduate Students, Student Research, Scientific Research, Genetics
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Murphy Angelo; Yash Bhargava; Scott Takeo Aoki – Biochemistry and Molecular Biology Education, 2024
The complexity of RNA cannot be fully expressed with the canonical A, C, G, and U alphabet. To date, over 170 distinct chemical modifications to RNA have been discovered in living systems. RNA modifications can profoundly impact the cellular outcomes of messenger RNAs (mRNAs), transfer and ribosomal RNAs, and noncoding RNAs. Additionally, aberrant…
Descriptors: Genetics, Biochemistry, Molecular Biology, College Science
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Jiro Kondo; Shota Nakamura – Journal of Chemical Education, 2023
The use of molecular models in chemistry and biochemistry classes is very effective in helping students understand covalent bonds and the chemical structure of molecules. However, conventional molecular models cannot represent intermolecular interactions such as hydrogen bonds and electrostatic interactions. Herein, we describe 3D printed…
Descriptors: Chemistry, Molecular Structure, Scientific Concepts, Biochemistry
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María Florencia Mosquillo; Gonzalo Scalese; Felipe Castro; Leticia Pérez-Díaz – Natural Sciences Education, 2024
An effective, practical approach for incorporating molecular biology tools to biology and biochemistry students is described. For 6 weeks, students are exposed to bacterial transformation, plasmid DNA purification and analysis, parasite transfection, ectopic expression of fluorescent proteins, fluorescence microscopy, and flow cytometry analysis.…
Descriptors: Active Learning, Student Projects, Science Education, Molecular Biology
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Stephanie A. Carr; Stephanie L. Mathews; Justin A. Pruneski; Nikolas M. Stasulli – Journal of Microbiology & Biology Education, 2024
In this article, we describe curricular materials developed to engage undergraduate students in evolutionary thinking around antibiotic resistance using the MEGA-plate experiment (Microbial Evolution and Growth Arena). This elegant and visual experiment, developed by the Kishony Lab, shows the development of antibiotic resistance on the timescale…
Descriptors: Biochemistry, Science Instruction, Laboratory Experiments, Drug Therapy
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Goodsell, David S.; Zardecki, Christine; Berman, Helen M.; Burley, Stephen K. – Biochemistry and Molecular Biology Education, 2020
For 20 years, Molecule of the Month articles have highlighted the functional stories of 3D structures found in the Protein Data Bank (PDB). The PDB is the primary archive of atomic structures of biological molecules, currently providing open access to more than 150,000 structures studied by researchers around the world. The wealth of knowledge…
Descriptors: Biochemistry, Molecular Structure, Archives, Genetics
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Keira D. Naff; Jeri L. Tyler; Dima H. Hamza; Jonathan D. White – Journal of Chemical Education, 2023
Structure--activity relationships are foundational concepts in biochemistry and drug design. Despite their importance, it can be difficult to create and execute laboratory activities that allow students to directly observe the interactions between small-molecule drugs and their biomolecular targets. Here, we report an activity that investigates…
Descriptors: Genetics, Undergraduate Students, Undergraduate Study, College Science
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Andrea C. Bardales; Quynh Vo; Dmitry M. Kolpashchikov – Journal of Chemical Education, 2024
It has been shown that active learning strategies are effective in teaching complex STEM concepts. In this study, we developed and implemented a laboratory experiment for teaching the concepts of Boolean logic gates, molecular beacon probes, molecular computing, DNA logic gates, microRNA, and molecular diagnosis of hepatocellular carcinoma, which…
Descriptors: Active Learning, STEM Education, Scientific Concepts, Concept Formation
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Hadi D. Arman; Tu M. Ho; Kaitlyn Varela; Cynthia S. Veliz; Richard B. Zanni; Armando Rodriguez; Zhiwei Wang; Francis K. Yoshimoto – Journal of Chemical Education, 2023
Eleven different laboratory experiments were designed and executed throughout a semester to provide a meaningful research experience for 23 undergraduate biochemistry majors at UTSA. The topic of the semester was based on the idea of exploring new aspects to enhance our understanding of how the human body uses cytochrome P450 enzymes to metabolize…
Descriptors: Biochemistry, Science Laboratories, Undergraduate Students, Undergraduate Study
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Ochs, Raymond – Biochemistry and Molecular Biology Education, 2019
Understanding redox reactions in biochemistry requires a clear grasp of three definitions: electron exchange, oxidation number, and oxygen atom insertion. Here, the electrochemical cell is explained for redox-active ions, introducing a new comparison between the measurement of midpoint potential and the measurement of initial velocity for enzymes.…
Descriptors: Biochemistry, Scientific Concepts, Concept Formation, Measurement
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Munyemana, Jean Jacques; Nsanganwimana, Florien; Gaparayi, Gaspard – Cypriot Journal of Educational Sciences, 2022
This study explored the Rwandan secondary students' opinions on learning biochemistry concepts covered in the Rwandan advanced level of secondary school biology curriculum, and the reasons behind the difficulty of the concepts. In this research, sequential exploratory mixed-method designs were adopted. The sample comprised 195 secondary school…
Descriptors: Foreign Countries, Secondary School Students, Student Attitudes, Knowledge Level
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Kocemba-Pilarczyk, Kinga A.; Bentke-Imiolek, Anna; Dudzik, Paulina – Biochemistry and Molecular Biology Education, 2021
The aim of this online workshop is to familiarize biomedical faculties students with the principle of RT-PCR method. The following assumption is made, students participating in the workshop: (1) are already familiar with the principle of PCR reaction; (2) can distinguish PCR from RT-PCR; (3) know the basic possibilities of using the above…
Descriptors: Medical Students, Biochemistry, Genetics, COVID-19
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Chandler, Morgan; Shevchenko, Oleg; Vivero-Escoto, Juan L.; Striplin, Caryn D.; Afonin, Kirill A. – Journal of Chemical Education, 2020
Communicating the flow of genetic information (DNA ? RNA ? protein) is not only a basis of biochemical education, but also is the essential foundation for understanding the complexity of biological processes. The described laboratory exercise demonstrates that the information encoded into different DNA sequences can be transformed into various…
Descriptors: Science Instruction, Biochemistry, Science Laboratories, Hands on Science
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Takor, Gaius; Morgan, Christopher E.; Chiu, Liang-Yuan; Kendrick, Nashea; Clark, Emily; Jaiswal, Rohan; Tolbert, Blanton S. – Journal of Chemical Education, 2020
Two-dimensional nuclear magnetic resonance (2D NMR) techniques are regularly used for the determination of RNA structures. In an effort to introduce advanced level students who are generally not acquainted with or exposed to these techniques, this work, which has been designed as a practicum, utilizes a combination of 2D NMR techniques to help…
Descriptors: College Science, Undergraduate Study, Thermodynamics, Spectroscopy
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Heineman, Richard H. – Biochemistry and Molecular Biology Education, 2018
These three biology songs can be used for educational purposes to teach about biochemical concepts. They touch on three different topics: (1) cancer progression and germ cells, (2) gene expression, promoters, and repressors, and (3) electronegativity and the biochemical basis of photosynthesis.
Descriptors: Singing, Genetics, Biology, Biochemistry
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