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Cohesion of Cortical Language Networks during Word Processing Is Predicted by a Common Polymorphism in the "SETBP1" Gene
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Rakhlin, Natalia; Landi, Nicole; Lee, Maria; Magnuson, James S.; Naumova, Oxana Yu.; Ovchinnikova, Irina V.; Grigorenko, Elena L. – New Directions for Child and Adolescent Development, 2020
The etiological mechanisms of the genetic underpinnings of developmental language disorder (DLD) are unknown, in part due to the behavioral heterogeneity of the disorder's manifestations. In this study, we explored an association between the SETBP1 gene (18q21.1), revealed in a genome-wide association study of DLD in a geographically isolated…
Descriptors: Genetics, Language Impairments, Developmental Delays, Correlation
The Language Phenotype of a Small Geographically Isolated Russian-Speaking Population: Implications for Genetic and Clinical Studies of Developmental Language Disorder
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Rakhlin, Natalia; Kornilov, Sergey A.; Palejev, Dean; Koposov, Roman A.; Chang, Joseph T.; Grigorenko, Elena L. – Applied Psycholinguistics, 2013
This article describes the results of an epidemiological study of developmental language disorder (DLD) in an isolated rural Russian population. We report an atypically high prevalence of DLD across all age groups when contrasted with a comparison population. The results are corroborated by a set of comparisons of school-aged children from the…
Descriptors: Genetics, Comparative Analysis, Effect Size, Verbal Ability