Spectroscopy is an integral part of chemical research, and the operation of any spectroscopic instrument is critical in chemical education. This study presents a low-cost, do-it-yourself (DIY) style spectrophotometer system that can be adapted for UV--vis spectrophotometry, fluorimetry, and atomic emission spectroscopy applications. The DIY system…

Mastering the complexity of the nervous system is essential for education programs in physiology, anatomy, and neuroscience. Students often struggle when learning somatosensory pathways, which convey information from sensory neurons to the somatosensory cortex in the brain. Active learning activities incorporating physical models have been shown…

The reconstruction of two-dimensional (2D) slices to three-dimensional (3D) digital anatomical models requires technical skills and software that are becoming increasingly important to the modern anatomist, but these skills are rarely taught in undergraduate science classrooms. Furthermore, learning opportunities that allow students to…

Synthesis of (Z)-alkenes is challenging because the (E) stereoisomers are usually more stable. Energy transfer photocatalysis has emerged as an efficient strategy for (E) [right arrow] (Z) alkene isomerization. We report the development of an advanced undergraduate laboratory experiment that introduces students to contemporary organic…

Teaching the three-dimensional structure of saccharides has consistently been a challenging aspect of organic chemistry courses, impeding students' ability to grasp more advanced topics in biochemistry and food chemistry. In this article, we designed and developed a novel d-glucopyranose model using 3D printing technology for the first time. This…

Metal-organic frameworks (MOFs) are porous materials composed of metal ions and organic ligands. These materials have garnered significant attention due to their wide-ranging applications, such as the capture of hazardous molecules, catalysis, production of value-added compounds, and detection of ions or molecules in water. Despite their immense…

In this second-semester organic chemistry lab experiment, students work collaboratively using a combination of chemical synthesis and NMR spectroscopy to investigate the diastereoselectivity associated with the Meerwein-Ponndorf-Verley (MPV) reduction of two ketone substrates having carbonyl groups flanked by an [alpha]-chiral carbon with…

Isothermal titration calorimetry (ITC) is the method of choice for thermodynamic binding profiling. As a label-free in-solution technique, ITC experiments do not require modified or immobilized proteins or ligands and hence can be performed under close-to-native environmental conditions. It directly follows the released heat of the molecular…

Normal phase thin layer chromatography is a widely taught technique in undergraduate organic chemistry laboratory courses. To understand how the technique works, students must have a strong conceptual understanding of polarity and intermolecular forces. Unfortunately, many students have misconceptions regarding how polarity and intermolecular…

Infrared (IR) spectra of biologically derived materials display distinct absorption bands correlating to individual macromolecules: protein, polysaccharide, lipid, and nucleic acids. A series of experiments aimed at teaching qualitative bioorganic spectroscopy using attenuated total reflectance (ATR) Fourier transform infrared (IR) with biological…

A mixture of salt water and isopropyl alcohol is immiscible, forming two separate liquids with the organic layer on top and aqueous layer on bottom. When universal indicator is added to such a mixture, all of the indicator compounds in the universal indicator preferentially dissolve in the alcohol--except for phenolphthalein at high pH. Mixtures…

Nanozyme is a kind of mimetic enzyme possessing unique properties of nanomaterials and catalytic functions of natural enzymes. The nanozymes have the characteristics of high catalytic efficiency and good stability and are widely utilized in medicine, chemical industry, food, agriculture, and environment. This laboratory experiment is designed for…

Electrochemistry represents a powerful sustainable method for chemical synthesis; however, its widespread application is limited due to the lack of exposure and appropriate basic training of synthetic chemists and engineers in electrochemistry and electrochemical engineering. The introduction of diverse laboratory practices to the current…

The great development of high-throughput molecular biology techniques and the consequent generation of massive data have made Bioinformatics essential for undergraduate Bioscience students. The importance of this scientific discipline is evidenced by the huge number of specialized publications, tools, and databases available. Training in…

Light and its spectrum are central concepts in many introductory physics, astronomy, geology, and conceptual physics courses. The Sun and its spectrum are usually primary examples, likely due to the Sun's everyday familiarity and the full spectrum it generates when dispersed. To enhance such discussions with a hands-on student activity, we've…