Arguing from evidence is one of eight key science practices in which students should engage. It is an essential component of science, yet students have difficulties with this practice. We describe a scaffolded claims-evidence-reasoning (CER) argumentation framework that is embedded within a new eight-week, freely available curriculum unit…

The goal of my dissertation was to fine map the milk yield and composition quantitative trait loci (QTL) mapped to cattle chromosome 3 (BTA3) by Heyen et al. (1999) and to identify candidate genes affecting these traits. To accomplish this, the region between "BL41" and "TGLA263" was mapped to the cattle genome sequence assembly Btau 3.1 and a…

Research in manipulation of genetic inheritance opens new vistas. Biologically-styled industrial synthesis is better in many respects than chemical engineering practices now in use. An approach for improving hereditary characters in living organisms without considering social implications is unwise. (PS)

Describes the rapid advance of molecular genetics over the past 20 years that have accounted for the origin of mutations. This research has revealed that variation within species is much greater than Darwin postulated. (Author/MA)

Can genetic evolution be controlled by man in a manner which does not violate a civilized, humane, and democratic ethos? The genetics of health and illhealth and of normal variation are discussed with respect to this question. (PEB)

Presented are issues related to genetic engineering. Increased knowledge of techniques to manipulate genes are apt to create confusion about moral values in relation to unborn babies and other living organisms on earth. Human beings may use this knowledge to disturb the balance maintained by nature. (PS)

Forty-two parents of children with autistic disorder, 15 children with autistic disorder, 17 siblings of children with autistic disorder, and 12 unrelated normal controls were studied for binding characteristics of their immunoglobulins. Results did not support the hypothesis that two specific autoantibodies are characteristic of autism.…

If the aim of new research is to improve the genetic inheritance of future generations, then decisions regarding who should decide what research should be done needs to be established. Positive and negative eugenics need to be considered thoroughly. (PS)

Manipulation of genes in human beings on a large scale is not possible under present conditions because it lacks economic potential and other attractions for industry. However, preventive'' genetic engineering may be a field for vast research in the future and will perhaps be approved by governments, parishes, people and industry. (PS)

The heritability of substance dependence (SD) liability is based on polymorphisms at the genes that are likely to be related to the function of the central nervous system. We have recently shown an association between the dopamine D5 receptor gene and SD liability. We report herein a replication of this association in an independent case-control…

The author explains that misunderstanding the role of science and scientists is mainly due to a communication gap precipitated by the enormity of the field of science. Among the many examples given are cloning and DNA from biomedical research. Argues strongly against establishing an agency to control the field of scientific research. (GA)

Describes the successful use of giving examples of genes affecting various steps in biochemical pathways to teach gene interaction. Finds that once students grasp the notion that genes can interact because they control different steps within biochemical pathways, the reason why phenotypic ratios appear to be non-Mendelian becomes more obvious and…

EIGHTY-FIVE BOOKS AND ARTICLES DEALING WITH DOWN'S SYNDROME (MONGOLISM) ARE LISTED. DATING FROM 1933 THROUGH 1965, THE ITEMS CITED FOCUS ON BIOCHEMICAL AND GENETIC FACTORS AS WELL AS THE DEVELOPMENT OF THE MONGOLOID CHILD. (JD)

Several hands-on and wet laboratory activities have been proposed to model the genetic concepts of genotypes and phenotypes and their relationship. The exercise presented in this article is a novel, time effective, student-centered, role-playing activity in which students learn about the intricate connection between genotype and phenotype by…

ADDRESSED TO PUBLIC HEALTH WORKERS AND PHYSICIANS IN GENERAL PRACTICE, THE PAMPHLET INTRODUCES METHODS OF DETECTING AND MANAGING PHENYLKETONURIA, AN INHERITED METABOLIC DISORDER ASSOCIATED WITH MENTAL RETARDATION. INFORMATION, UPDATED FROM THE 1961 EDITION, IS INCLUDED ON THE INCIDENCE AND GENETICS, BIOCHEMISTRY, AND CLINICAL COURSE OF THE…