Assessment in institutions of higher learning has been researched worldwide. However, there are gaps in research exploring the implications of assessment practices for learners' access to the kind of knowledge enabling them to participate in their communities' socio-economic transformation. This is the case in the African Great Lakes region, including Rwanda. This paper investigated the assessment practices at the University of Rwanda-College of Education to establish whether they enable students to access powerful knowledge for socio-economic transformation, which promotes critical thinking and creativity, or the knowledge of the powerful, which promotes memorization of knowledge produced by experts. The study adopted mixed methods, where 361 questions from 20 examinations papers for 2014/2015 and 2015/2016 academic years were analysed using Bloom's revised taxonomy. Interviews with lecturers and group discussions with students were conducted. The findings revealed that assessment practices heavily encourage the knowledge of the powerful, with limited focus on the socio-economic transformative knowledge. Such practices are unlikely to lead to national socioeconomic transformation, which the government expects from education. The paper recommends revisiting assessment practices in Rwandan higher education to instil in the graduates the required knowledge for active contribution to socio-economic transformation.