Introduction: Down Syndrome (DS) is a common cause of intellectual disability with a possible glial-neuronal disruption. We assessed the effects of Cerebrolysin on the neurodevelopmental outcomes of infants with DS. Methods: This randomized controlled pilot trial included 64 infants with DS. They were allocated into a treatment group (n=32) who…

The objective of this study was to verify the effects on 4- to 18-month-old babies' NPMD after the family-centered Kids Intervention Therapy -- Aquatic Environment (KITE) programme. This quasi-experimental study involved 61 families. The NPMD was assessed with Alberta Infant Motor Scale (AIMS), Denver II Developmental Screening Test, context…

Purpose: This study tested whether the Sitting Together and Reaching to Play (START-Play) physical therapy intervention indirectly impacts cognition through changes in perceptual-motor skills in infants with motor delays. Methods: Participants were 50 infants with motor delays randomly assigned to START-Play plus Usual Care Early Intervention…

Aims: Children with neuromotor delays are at risk for reaching and object exploration impairments, which may negatively affect their cognitive development and daily activity performance. This study evaluated the effectiveness of the Sitting Together And Reaching To Play (START-Play) intervention on reaching-related exploratory behaviors in…

This study aims at checking the effects of an early intervention program (EIP) on the neuropsychomotor development (NPMD) and quality of life (QoL) of 4-18 months old babies attending daycare, following the biopsychosocial (BPS) model of health and the International Classification of Functioning Disability and Health (ICF). It was a…

In the United States, early intervention (EI) programs under Part C of the Individuals with Disabilities Education Act serve thousands of infants and toddlers with or at risk for developmental delays. Despite this, few studies have investigated the developmental progress and outcomes of children served, especially in relation to the heterogeneity…

Although Baby Sign is gaining in popularity, there is a scarcity of research supporting its use. The research that has been conducted is conflicting. In the current study, nine families with children ranging in age from six months to two years and five months participated in a baby sign workshop. A pre--post-test design was used to assess the…

Aim: The aim of this study was to evaluate cognitive and motor development in children with major congenital anomalies and the predictability of development at age 5 years. Method: A prospective, longitudinal follow-up study was undertaken. The Dutch version of the Bayley Scales of Infant Development--Mental Developmental Index (MDI) and…

An early intervention program for 14 Down's syndrome children (4 to 15 months old) and their parents included individualized guidance for parents in teaching their infant. Home activities centered on tasks to develop attention: cognitive, perceptual, motor, and language skills. Emphasis was placed on a structured teaching approach with…

Two techniques to normalize muscle tone were evaluated with nine infants and young children with cerebral palsy who were enrolled in the Rural Infant Stimulation Environment (RISE) Program, near Tuscaloosa, Alabama. Electromyography (EMG) and skin temperature data were used to assess the effects of trunk rotation and slow rolling on a ball. EMG…

An intensive early intervention program was evaluated by assessing gains made by 44 special needs children (age 2) in cognition, gross motor, fine motor, receptive language, and expressive language domains. Comparison of actual to predicted posttest scores did not reveal significant gains in any domains. In cognition, gross motor, and fine motor…