Almost three million records covering approximately 175,000 chemical compounds and involving multiple disciplines have been recorded in the Army Antimalarial Drug Program. Maximum compartmentalization of files together with a complete method of interfacing files and a unique number system has made it possible to manage this system. (2 references)…

Two systems, WLN and Ringcode, for retrieving structural information were analyzed qualitatively and evaluated for a series of chemical compounds. The studies ranged from specific to generic questions and also involved retrieval by fragments. Neither system was completely satisfactory for all types of searches. (6 references) (Author)

A design is described for a system to manage the information directly related to the experimental work in a toxicological laboratory. A number of distinct input procedures provide data to a set of co-existing data bases. Periodic, event-triggered, predefined demand, and ad hoc reports are posited. (12 references) (Author/NH)

Among other improvements in chemical nomenclature used in the Chemical Registry System, Chemical Abstracts Service intends to standardize the fundamental principles for naming cyclic structures so that procedures for the derivation of ring names can become more amenable to computer generation and translation. (Author/NH)

The Multiterm system is shown to be a unique concept for producing a multilingual index via computer processing. The new concept has significance for international cooperative programs. (6 references) (Author/NH)

A computer system, named CORA, has been devised for coding chemical structures by fragmentation elements. It has been used to encode Markush formulas in patents according to the Ring codes used in the Ringdoc and Pestdoc services and results in an easy, speedy, reliable and inexpensive method. (4 references) (Author)

A formula is given that enables one to determine the parameters for amortizing an information system within a year. The formula is illustrated with three mechanized information systems for patents. The most critical parameter is shown to be indexing time. (7 references) (Author/NH)

Minimum, maximum, and average lengths and frequency counts for the data elements in the Chemical Substance and General Subject segments of the Standard Distribution Format (SDF) files distributed by Chemical Abstracts Service are presented. (5 references) (Authors)

The state of the art for document access is briefly reviewed and a reasonably far look into the future is presented in this paper. (40 references) (Author/NH)